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Biomedical subjects

O Doi

Publications and source records attributed to O Doi.

At least 127 records · Page 7Linked to original sources
PubMed1986

[Indications for surgical resection of lung metastasis from breast cancer--considerations according to the mechanism of extension of metastases].

The indications for surgical treatment of lung metastasis from breast cancer were analyzed according to the extension mode of the metastasis. Of lung lesions that seemed operable roentgenographically at the time of their first manifestation, about half developed new metastatic nodules within six months thereafter, while the other half did not do so for more than two years. No clinicopathologic findings at the time of mastectomy were helpful to differentiate the two groups, except that a cancer-free interval of less than a year fell exclusively into the former group. Thus, the only way to determine the indications is to watch the lesions for six months with chemo-endocrine therapy.

Breast Neoplasms↗
PubMed1985

[Chemo-hyperthermotherapy following thoracic surgery].

Local radiofrequency hyperthermia combined with chemotherapy was performed on patients with thoracic malignancy, who had under gone non-curative resection because of disseminated pleural involvement or positive surgical margin, and who had metastatic lesions (after curative surgery). In some patients, subjective symptoms were decreased or tumor necrosis was proved cytologically. This therapy may therefore be useful for patients with thoracic malignancy.

Aged↗
PubMed1983

Photoperiodic regulation of serotonin N-acetyltransferase activity in the pineal gland of the chicken.

1. In continuous light, serotonin N-acetyltransferase activity in the pineal gland of 16-day-old chicks was reduced to about a half of the usual nocturnal level only in the first day, but no suppressive effect by the light was observed throughout the following 2 days. 2. In continuous darkness, circadian N-acetyltransferase rhythm persisted for three consecutive days. 3. In continuous light, the phase of N-acetyltransferase rhythm in chick pineal delayed remarkably for three consecutive days, while the phase delayed in a lesser degree in continuous darkness. 4. The rhythm of N-acetyltransferase activity in the pineal gland of 13-day-old chicks was entrainable to a shorter (8L: 8D) and a longer (18L: 18D) photoperiod as in a 12L: 12D photoperiod, but a shorter photoperiod such as a 3L: 3D photoperiod failed to change the pre-established 12L: 12D rhythm.

Acetyltransferases↗