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O Dorobăţ

Publications and source records attributed to O Dorobăţ.

At least 19 recordsLinked to original sources

[Rapid methods useful for determination of streptococcal groups with special reference to streptococci of groups B and D].

A study was carried out on the efficiency of certain rapid methods for the identification of streptococcal groups, especially groups B and D, methods based upon physiologic properties such as hippurate hydrolysis, production of pigment, esculin hydrolysis, tolerance to salt and bilolysis, associated with the classical tests, for instance the hemolysis type and sensitivity to bacitracin and optochin. By these tests, accessible to hospital laboratories, a number of 3083 streptococcal strains were correctly identified within 2 to 18 hours, of which 2567 group A, 31 group B, 184 group C, G, 113 group D, 155 Str. pneumoniae and 31 viridans, strains isolated from pathological products.

Bacitracin↗

Characteristics of Neisseria meningitidis strains isolated in Romania between 1986 and 1989.

499 N. meningitidis strains were studied, 454 being isolated from CSF and blood and 45 from nasopharynx. Meningococcal serogroup A was prevalent in 1986-1988, having a decreasing tendency from 84.90% in 1987 to 45.0% in 1989. Serogroup C increased from 0.86% in 1986 to 15% in 1989. All strains, examined by diffusiometric method, were sensitive to ampicillin, cephalotin, chloramphenicol and rifampin. For tetracycline, resistance ranged from 2.28 to 6.0% in 1987-1989. The frequency of 52.0-72.14% resistant to sulphamides strains seems to be due to serogroup A prevalence. Six N. meningitidis strains, isolated in 1989, proved to be moderately resistant to penicillin with MIC greater than or equal to 0.1 mcg/ml. The results indicate the necessity of a continuous surveillance of meningococcal infection, both from the point of view of serogroup circulation and also of antibiotics sensitivity.

Anti-Bacterial Agents↗

Diagnosis of pneumococcal meningitis by coagglutination method.

It was tested the possibility to evidence the pneumococcal capsular antigen, by coagglutination, directly in CSF, using a specific coagglutinating reagent for all the 10 serological types of S. pneumoniae more frequently encountered in our country. Were investigated 134 CSF from purulent meningitis, out of which 37 were of probable pneumococcal etiology, on the basis of bacterioscopic examination, 26 of other etiology and 71 of unknown etiology. The results obtained showed 28 (75.7%) positive reactions in the fluids from probably pneumococcal meningitides on the basis of the positive bacterioscopic examination. The specificity of the reactions is demonstrated by the negative reactions with the fluids from meningitides of other etiology, as well as by the concordance between the antigen serotype from the liquid and that of the isolated S. pneumoniae strain. For a good test sensitivity could argue the positive reactions obtained with 6 CSF from meningitides of unknown etiology.

Agglutination Tests↗

[Staphylococcus saprophyticus isolated in blood cultures from normal-weight newborn infants with septic arthritis].

The paper deals with the identification of some Staphylococcus saprophyticus strains received by the Staphylococcus National Reference Centre, in the Cantacuzino Institute, Bucharest, Romania. The strains were isolated from blood cultures pre-elevated in a maternity in Bucharest from normoponderal newborns with septic arthritis. Recent data from literature concerning the infections caused by coagulase negative staphylococci in general, with special reference to those cause by S. saprophyticus are presented. The identification scheme used in the Cantacuzino Institute and the minimal microbiological diagnosis tests of S. saprophyticus recommended to the clinical laboratories by the International Society for the Taxonomy of Staphylococci and Micrococci are also described.

Anti-Bacterial Agents↗