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Biomedical subjects

O E Böe

Publications and source records attributed to O E Böe.

15 recordsLinked to original sources

Effects of topical metronidazole and tetracycline in treatment of adult periodontitis.

The present study was performed to assess and compare the clinical healing and the microbiological findings following local application of metronidazole or tetracycline to augment subgingival scaling in previously untreated adult periodontitis sites. Eighteen patients with moderate to severe adult periodontitis at single-rooted teeth were selected. In each patient, 3 interproximal sites having comparable root anatomy, probing depth > or =5 mm and bleeding on probing were randomly assigned to 1 of 3 treatment groups: 1) two sessions of subgingival scaling and root planing; 2) similar to 1, with each treatment supplemented with a 25% metronidazole sustained release gel; 3) similar to 1 with each treatment supplemented with a 3% tetracycline ointment. The treatments were performed by 1 operator and the clinical variables probing depth, attachment level, and bleeding on probing were evaluated at baseline, 3 months and 6 months by a second blinded examiner. The microbiological findings were evaluated using a commercial test kit. The average probing depth reduction for the 3 groups at 6 months was 1.5 mm and the average gain of clinical attachment was 0.8 mm. There were no significant differences between the effects following topical application of the metronidazole gel or the tetracycline ointment. Scaling and root planing alone appeared as effective as the drug augmented regimens, although there was a weak but non-significant tendency for better results in sites treated with the antibiotic drugs. Actinobacillus actinomycetemcomitans was generally not detected; Prevotella intermedia was not significantly reduced, while Porphyromonas gingivalis was significantly reduced in all treatment groups. It was concluded that the augmentative effect of the metronidazole gel and the tetracycline ointment was comparable but small compared to scaling and root planing alone. The clinical importance of such small augmentation effects should be further evaluated.

Administration, Topical↗

A correlation study of inflammatory cell mobilization in response to subgingival microbial colonization.

This study evaluated site-by-site the relations between subgingival microbial colonization and gingival tissue reactions. Experimental, deep periodontal defects were established at buccal surfaces of mandibular and maxillary canine teeth in 5 beagle dogs. The root surfaces were instrumented by a flame-shaped, fine-grained, rotating diamond point, or by a sharp curet. Following a 10-day postsurgical healing period, the dogs were fed a plaque-inducing diet for 70 days. The animals were then sacrificed and tissue blocks of the experimental sites including teeth and periodontal tissues were secured. The buccal gingiva was removed and processed for histomorphometric analysis while the teeth were prepared for scanning electron microscopic evaluation of the extent of subgingival microbial colonization. The results revealed that inflammatory cell density in the junctional epithelium and in the connective tissue were positively correlated to subgingival microbial colonization (P < 0.01). Furthermore, the degree of significance decreased with increasing distance from the plaque. The present study demonstrates that a close relation may exist between the extent of subgingival microbial colonization and inflammatory gingival tissue reactions.

Animals↗

Influence of tooth instrumentation roughness on gingival tissue reactions.

Histological studies have demonstrated a relationship between the amount of subgingival plaque and the magnitude and extension of gingival tissue reactions. The objective of the present study was to evaluate inflammatory reactions in the gingival tissues facing plaque accumulation at a diamond and curet-instrumented root surfaces. Experimental, deep periodontal defects were established at buccal surfaces of mandibular and maxillary canine teeth in 5 beagle dogs. The root surfaces were instrumented by a flame-shaped, fine-grained. rotating diamond point, or by a sharp curet. Next, the dogs were fed a plaque-inducing diet for 70 days. The animals were then sacrificed, and tissue blocks of the experimental sites including teeth, alveolar bone, and gingival tissues were secured. The gingival soft tissue was processed for histomorphometric analyses at 3 levels. Epithelium and connective tissue area measurements showed no differences between the two instrumentations. Junctional epithelium (JE) cell point counts exhibited a higher proportion of inflammatory cells (IC)in specimens facing diamond compared to curet-instrumented defects. A higher proportion of IC was present within the coronal compared to the apical aspect of the JE for both instrumentations (P < 0.05). A significant difference in IC density between instrumentations was detected for non-infiltrated (P < 0.05), as well as for infiltrated (P < 0.01) connective tissue. The infiltrated connective tissue (ICT) inflammatory cell density was significantly (P < 0.01) and positively correlated to the JE inflammatory cell density (r = 0.75), and to area measurements of ICT (r = 0.55). The overall results demonstrate that the character of subgingival root instrumentations significantly affects gingival inflammatory reactions, most likely by influencing subgingival plaque formation.

Alveolar Process↗

Prevalence of malocclusion and need for orthodontic treatment in Saudi Arabia.

The prevalence of different malocclusion features was investigated in 500 14-yr-old male Saudi Arabian children, using a modification of the registration method described by Björk et al. (3). Most of the children were in dental stage DS4 (all permanent teeth anterior to the first molars erupted). Totally 62.4% of the children had one or more malocclusion features related to dentition, occlusion, or space. The treatment need was evaluated according to the guidelines used in the Norwegian Health Service. About 40% were found to need treatment with fixed appliances, and for 33% extraction of permanent teeth would be part of the treatment. Only about 2.5% would benefit from treatment with simple removable appliances.

Adolescent↗

Periodontal health in a group of industrial employees.

The aim of this study was to evaluate the dental health conditions of male employees in a large aluminum factory. The present report deals only with the periodontal findings. Five percent of the 181 examined subjects between 25 and 60 yr were edentulous, and all dentate individuals had some degree of periodontal disease. Surfaces harboring stainable plaque were high in all age groups, varying between 65 and 85%. Surfaces without retention factors were 31% and decreased with increasing age. The percentage of sites with bleeding increased from about 40% in the lowest to about 60% in the highest age group. Teeth with probing depths greater than or equal to 4 mm increased from about 30% in the age group 25-29 yr to about 45% in the age group 30-34 yr, after which it increased gradually with increasing age. The difference in bone scores (marginal bone loss) was the most extensive between the ages of 25 and 34 yr, but with a significant increase throughout the age groups. The administrators had a somewhat better oral hygiene, fewer retention factors, less bleeding, fewer pockets and some more marginal bone support than the workers. Still, the administrators had more missing teeth than the workers.

Adult↗

Dental health of young Vietnamese immigrants.

About 3000 refugees from Vietnam have come to Norway in the last 5 years. A survey, including a clinical and radiographic examination for caries and gingival health, was carried out on 142 refugees. They were aged from 2 to 18 years and were examined within 6 weeks of arrival in Norway. The mean dmfs score of subjects 2-5 years old was 23.9, for subjects 6-11, dmfs was 12.4 and DMFS 7.7, and for subjects 12-18, DMFS was 20.0. The dmf/DMF scores were mainly composed of caries grades 3 and 4 (dentin caries or caries with pulpal involvement), and teeth missing or indicated for extraction. Only eight subjects had restorations, and these were often of poor quality. All subjects over 6 years had gingivitis (GBI 62%). About 10% had enamel hypoplasias on permanent anterior teeth. Dental abscesses and periapical areas indicated an acute treatment need, and most subjects were in urgent need of restorative treatment. Average time required for treatment of 12-18-year-old patients is estimated to be 7-10 hours, about four times that required for Norwegian schoolchildren. Dental examination of newly arrived Vietnamese refugees is recommended.

Adolescent↗

Floating norms as guidance for the position of the lower incisors.

1. The incisor position should be evaluated in relation to the sagittal and vertical configurations of the face, as well as to the shape of the bony chin. 2. A floating norm for the positioning of the lower incisors is established based upon the guiding variables ANB, ML-NL and the N angle with the introduction of a multiple regression equation. The anticipated values for the guiding variables at the end of the treatment are used in the calculation.

Adult↗

Mandibular anterior crowding in relation to tooth size and craniofacial morphology.

In the present study the problem of mandibular anterior crowding was investigated by comparing a group of adults having approximately ideal occlusion (n = 27) with a group with corresponding occlusion except for a slight crowding in the mandibular anterior segment (n = 39). Both sexes were represented. A statistical evaluation revealed that in the latter group the mesiodistal diameter of the four mandibular incisor teeth was significantly greater, whereas the intercanine width and the frequency of third molars were the same in both groups. A comparison of the craniofacial morphology of the two groups displayed limited differences, and only the basal sagittal jaw relationship and the mandibular inclination differed significantly. No significant correlations were observed between the space conditions and any of the variables studied.

Adult↗