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Biomedical subjects

O E Rodermund

Publications and source records attributed to O E Rodermund.

At least 19 recordsLinked to original sources
PubMed1979

Comparison of three methods of susceptibility testing of bacteroidaceae, peptococcaceae and other anaerobes to doxycycline.

The in vitro activity of doxycycline against 147 strains of gram-positive and gram-negative anaerobes was determined by broth dilution, agar dilution and agar diffusion tests. The strains were isolated from clinical specimens in 1977. Saccharolytic Bacteroides strains (39 B. fragilis, 6 B. thetaiotaomicron, 4 B. vulgatus) showed broth dilution MICs of less than or equal to 0.0625-4.0 microgram/ml after 5 h incubation and MICs of less than or equal to 16 microgram/ml after 15 h incubation at 37 degrees C. With strains of B. oralis, B. melaninogenicus ss. intermedius, B. corrodens, Veillonella sp. and Megasphaera elsdenii the broth dilution MICs were less than or equal to 0.0625-32 microgram/ml after 15 h incubation. Peptostreptococcus spp., Propionibacterium acnes, Eubacterium sp., Bifidobacterium sp. and Clostridium sp. had broth dilution MICs of less than or equal to 2 microgram/ml, whereas Peptococcus spp. were inhibited by less than or equal to 0.0625 to greater than 32 microgram/ml. With the great majority of strains tested, MICs were 2 to 256 times higher in agar than in broth dilution tests. Clinical and experimental studies seem to be needed to determine which of the in vitro data are correlated to the outcome of doxycycline therapy. Several groups and species were separately considered for statistical analysis of the relationship between zone size and MIC. With gram-positive anaerobes, correlation was poor between broth dilution MIC and zone size (correlation coefficients r = - 0.168 for Peptococcaceae, and r = - 0.108 for P. acnes). When calculating the regression lines for agar dilution MICs and zone diameters, a higher correlation was found (r = - 0.9 for Peptococcaceae; r = - 0.397 for P. acnes). With B. fragilis and other Bacteroides species correlation coefficients were r = - 0.807 to r = - 0.891 for broth and agar dilution MICs and zone size but stochastic linearity was lacking.

Anaerobiosis↗
PubMed1978

[Bloom syndrome: review and definition].

The cases of Bloom-syndrome as described in the literature (till...) are reviewed and this syndrome is discussed as a defined entity which can be separated from congenital poikilodermias. The prognosis of this autosomal recessive disease is dubious.

Abnormalities, Multiple↗
PubMed1978

[So-called nevoid forms of congenital poikiloderma].

The nevoid forms of poikilodermia as described in the literature are reviewed. The cases presented can be classified in better defined entities. The significance of a nevoid form of poikilodermia is doubted.

Abnormalities, Multiple↗
PubMed1978

[Esophageal manometry in Behçet's disease (author's transl)].

Esophageal function was investigated by quantitative intraluminal pressure measurements in three patients with Behçet's disease. All three had motility disorders partially resembling those described in diabetics and partially those from patients with scleroderma. These motility disturbances may be secondary to a neurological involvement in Behçet's disease.

Behcet Syndrome↗
PubMed1978

[Tuberculosis of seminal vesicle. A contribution to differential diagnosis of fructose deficiency in spermatic fluid (author's transl)].

The functional condition of seminal vesicles can be judged on the basis of spermatic fructose. In dealing with the causes of fructose deficiency, one must distinguish between androgen-dependent and androgen-refractory deficiencies. The main causes of androgenic-refractory fructose deficiency are specific and unspecific inflammations of the masculine adnexa. The example of spermatocystic tuberculosis demonstrates the importance which must be given to specific inflammation of the masculine adnexa, during fertility-consultation hours.

Adult↗
PubMed1978

[Scintigraphic changes on the liver and spleen in urticaria pigmentosa].

In 36 patients with mastocytosis pathological changes in liver and spleen were scintigraphically demonstrated. These changes are due to the histologically proven involvement of the reticuloendothelial system. The infiltration of the liver by mast cells was not evident in liver biopsy.

Adolescent↗
PubMed1977

[Report of a case of Goltz-Gorlin syndrome].

A case of Goltz-Gorlin-syndrome (congenital ectodermal and mesodermal dysplasia) in a 8 1/2 year old girl with focal dermal aplasia after birth, poikilodermia, anomalies of nails, hair, teeth, eyes and bones is presented.

Abnormalities, Multiple↗