[Reaction of organic lithium compounds with derivatives of 1,8-dihydroxyanthraquinone (author's transl)].
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Biomedical subjects
Publications and source records attributed to O E Schultz.
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Calculating the protein binding of six drug series the value sigma/sigma net charge/Mol turned out to be characteristic if the effects of substitutents were considered. Single- and multiple-substituted compounds were calculated in separate groups. For aliphatic-substituted compounds a classification resulted from the length of the substituted chain and from characteristic atoms. Substitution in 3- or 4-position made no significant differences. As an additional value sigma SAP/Mol may be applied to aromatic-substituted compounds.
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