Ligation of the artery of the dog sinoatrial node.
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Biomedical subjects
Publications and source records attributed to O Eliska.
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THE LYMPHATIC VESSELS OF THE SINU-ATRIAL (SA) node were investigated after injection of Indian ink plus gelatine in 62 canine and 31 human hearts, the latter of subjects aged between 21 and 80. Lymph was found to be chiefly drained from the SA node of the dog by a vessel which collected lymph near the left margin of the SA node and ran between the superior vena cava and the right circumference of the aorta into the left cardiac lymph collector and through it into the left cardiac node. Approximately in two thirds of cases this main lymph drainage was supplemented by smaller lymphatic branches running into the right traceo-bronchial nodes. In man, the main route of lymph drainage from the SA node is represented by one or two vessels which run to the right and upwards along the superior vena cava into the inferior tracheo-bronchial nodes (of the bifurcation), lying near the right bronchus. Little branches draining lymph into the cardiac collector are found rarely. It has become evident from histological sections that the lymphatic vessels run between the cells of the conduction system and the collagenous fibres of connective tissue and are not numerous.
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The efferent lymphatic vessels of the heart were ligated in 35 dogs and afterwards the systems of lymphatic and blood vessels were filled with various media by injection. Twelve of these dogs were sacrificed 30 min. after ligature and the remaining 23 dogs were left to survive for two to 132 days. After acute ligature of lymph routes, no lymphatic anastomoses could be found. In the protracted experiment, lympho-lymphatic anastomoses had developed between the interrupted trunks and very thin ones at the sites of adhesions between the epicardium and pericardium by the seventh to 14th day. In five out of 23 dogs, lymphovenous anastomoses of a calibre of 40-60 mum. were found between the seventh and 28th day after ligature. After one month, these LVA could no longer be found. Both forms of anastomoses, i.e. lympho-lymphatic and lymphovenous, may be present at the same time. The mutual relationship between these forms was discussed in the paper.
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