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Biomedical subjects

O F GRIMES

Publications and source records attributed to O F GRIMES.

49 records · Page 3Linked to original sources
PubMed1952

Carcinoma of the colon.

In a study of statistical data on 1,215 patients with carcinoma of the colon observed at a university hospital in a twenty-year period, it was noted that the overwhelming majority of patients who were living five years after operation had had no demonstrable extension to lymph nodes at the time of operation. In an increasing proportion of cases in the latter years of the period, diagnosis was made before the lesion was beyond an operable stage. What with today's better surgical techniques that make it possible to adapt operation to a variety of situations that may be encountered when the diseased area is visualized, and with better methods of preparing a patient and of sustaining him during operation, the wide excision so often necessary for cure may now be carried out deliberately and without hurry. The site of the lesion has great bearing on the prognosis, owing to the limits upon the extent of operation in some locations as against the possibility of wide excision of the original lesion and areas of metastasis in others.

Carcinoma↗
PubMed1952

The early diagnosis of carcinoma of the stomach.

The insidious nature of carcinoma of the stomach has induced a pessimistic attitude in the medical profession, for by the time the unmistakable signs of malignant disease become evident, the patient is doomed. Improvement in results of the surgical treatment of gastric carcinoma will come only with early diagnosis, which is in turn dependent upon appreciation of the gravity of recognizable epigastric distress and the application of the available diagnostic procedures to aid in the diagnosis of malignant lesions in the early, preinvasive stages. Recognition of the significant risk of malignant change in gastric ulcers is essential, for a high degree of suspicion in the presence of the symptoms of ulcer can lead to diagnosis of malignant lesions at a stage when resection can cure.

Carcinoma↗
PubMed1950

Gastric resection; preoperative and postoperative care.

Perhaps in no other field of surgery does attention to minute detail play so important a role in determining success as it does in gastric operations. As surgery of the stomach develops toward even greater security and favorable results can be expected with greater confidence, the several aspects of preoperative and postoperative care hitherto regarded as secondary demand closer consideration.

Gastrectomy↗