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Biomedical subjects

O FITZGERALD

Publications and source records attributed to O FITZGERALD.

At least 19 recordsLinked to original sources
PubMed1963

A CLINICAL STUDY OF CHRONIC PANCREATITIS.

A series of 53 cases of chronic pancreatic disease is described and attention drawn to the frequency with which symptoms are persistent rather than intermittent. A plea is made for the use of the term ;progressive' rather than ;relapsing' in describing many of these cases. Alcohol was an unimportant factor in the aetiology. The possibility of achieving an accurate and early diagnosis using the serum secretin/pancreozymin test is emphasized. The frequent relief of symptoms and the prevention of progress of the disease by surgery, especially sphincterotomy, is recorded.

Aged↗
PubMed1962

Serum studies in man after administration of vitamin A acetate and vitamin A alcohol. II. In subjects suffering from disturbances of absorption and digestion.

Vitamin A acetate and vitamin A alcohol, triolein I(131), oleic acid I(131), and fat balance tests have been assessed in studies on cases of coeliac disease, pancreatic insufficiency, and some disorders of the small intestinal wall. In coeliac disease a very low serum carotene and flat vitamin A absorption curves have been noted. The contrast between vitamin A acetate and alcohol curves has been clearly shown in cases of pancreatic disorder showing maldigestion. The correlation between vitamin A and triolein I(131) absorption (0.89) is closer than that between vitamin A and fat balance. In assessing intestinal absorption serum carotene figures are of value only if very low figures are found.

Alcohols↗
PubMed1962

Studies on the stability of vitamin A in the stomach and small intestine.

The instability of vitamin A alcohol relative to vitamin A acetate has been studied in vivo and in vitro. Vitamin A alcohol is more unstable than vitamin A acetate in human gastric and duodenal juice and in rats' stomachs and intestines and is more marked at lower pH levels and in rats' stomachs. Alpha tocopherol improved the absorption curve of vitamin A alcohol in man by protecting it in gastric and duodenal juice. This protective effect could not be demonstrated in the rat.

Animals↗