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Biomedical subjects

O Fischman

Publications and source records attributed to O Fischman.

At least 37 records · Page 2Linked to original sources

Experimental protothecosis in labortory animals.

Attemps were made to produce protothecosis in laboratory animals by intratesticular, intraperitoneal, intravenous and subcutaneous inoculation of Prototheca zopfii, P. wickerhamii and P stagnorta. Only intratesticular injection successfully caused infection, and of the inoculated protothecae, only P. zopfii and P. wickerhamii were recovered in culture from testicular material.

Animals↗

Prototheca stagnora, an encapsulated organism.

The type species of Prototheca stagnora, SEC-L-1690 (ATCC 16528) (2) was found to have a large capsule surrounding the cells, in India ink preparations. Cryptococcus neoformans and P. stagnora are very similar organisms in their morphology and they should be differentiated by their reproduction process or by their biochemical and physiological characteristics.

Cell Wall↗

Trichophyton mentagrophytes infection in laboratory white mice.

Trichophyton mentagrophytes infection was studied in a breeding colony of 42 white mice. Symptoms were observed in only 3 out of the 12 animals shown to carry dermatophyte on their coats. Literature on Trichophyton mentagrophytes infection mice is reviewed. The use of the technique developed by Mariat & Tapia (16) to isolate dermatophytes on cultures, specially for epidemiological surveys, is postulated. Attention is called to the importance of healthy animals, directly or indirectly, as carriers of fungi and sources of infection to other animals and human beings.

Animals↗

Paracoccidioidomycosis with palpebral and conjunctival involvement.

A case of pulmonary and lymphatic paracoccidioidomycosis followed by conjunctivo-palpebral involvement is studied in Sao Paulo (Brazil). The Brazilian literature is reviewed. The most frequent clinic forms of ocular lesions in natural infection are described. The small number of human cases observed is discussed. The severity and frequency of ocular lesions in experimental animals, intracardiacally inoculated with P. brasilensis cultures suggest haematogenic ocular dissemination of the fungus, which may occur in the septicemic stage of the human paracoccidioidomycosis.

Adult↗