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Biomedical subjects

O G Brooke

Publications and source records attributed to O G Brooke.

14 recordsLinked to original sources
PubMed1979

Energy retention, energy expenditure, and growth in healthy immature infants.

Energy balance studies were done during 10-29 days on 15 immature infants of mean birth weight 1581 g. Mean gross energy intake was 757 kJ/kg (181 kcal) and 79% of this was retained, so that metabolizable energy was 602 kJ/kg (143 kcal). Mean resting metabolic rate was 244 kJ/kg (58.1 kcal), and it increased with advancing maturity. Minimum resting metabolism averaged 199 kJ/kg (47.5 kcal). Energy expended in activity increased with maturity, but amounted to less than 17% of the total energy turnover. Postprandial metabolism caused the mean VO2 to rise by 17% in the hour after a feed, and during 24 hr resulted in consumption of energy equivalent to about 10% of the resting metabolism. Stored energy amounted to 230 kJ/kg (55 kcal) and was linearly related to weight gain (r = 0.92). Energy cost of weight gain was 24 kJ/g (5.7 kcal) and energy stored in new tissue was 16.8 kJ/g (4.0 kcal). Maintenance energy requirement at zero growth rate was about 270 kJ/kg (64 kcal).

Energy Metabolism↗
PubMed1978

Fetal growth in different racial groups.

Three racial groups of mothers and their newborn babies-- North European 75, Negro 75, and "Indian" Asian 37--were matched for parity, gestational age, sex, maternal age, maternal smoking habits, and social class. Multiple anthropometric measurements, including skinfold thickness, limb circumferences, and various linear measurements were made on the mothers and their infants to determine the effects of race and smoking on fetal size. Indian-Asian mothers, though shorter and lighter than Europeans and Negroes, had similar skinfold thickness and weight: height2 ratios and gained as much weight during pregnancy. Their infants, however, were lighter than the others, and had smaller head and limb circumferences, although their linear measurements were the same. Negro and European infants were almost identical in size. We found no effect on any of the fetal measurements which could be attributed to smoking.

Adult↗
PubMed1978

Loss of energy during continuous infusions of breast milk.

During 9 experiments simulating continuous intragastric infusion of human breast milk, variations in milk energy content of up to 24% occurred, the samples taken at the end of 8-12 hours' infusion being particularly energy-rich compared with earlier samples. Burettes should be regularly agitated during infusions of human milk.

Calorimetry↗
PubMed1976

High energy feeding in protein-energy malnutrition.

The use of a high-fat diet in malnourished children produced accelerated growth of lean tissues as well as adipose tissue, and resulted in rapid nutirtional rehabilitation in 25 seriously malnourished babies. Such diets are easy to prepare and relatively cheap, and they offer important advantages over conventional feeding in the hospital treatment of malnourished children.

Body Weight↗
PubMed1975

Measurement of deep body temperature from the urine.

1. The relation between urine and rectal temperatures has been studied under a variety of conditions by using the Uritemp bottle, which measures deep body temperature from the urine. 2. This device gives a reliable measurement of deep body temperature and has advantages over both rectal and oral techniques for many clinical applications. 3. The development of a new and more reliable device, the Uritemp meter, is described. Urine is voided through a specially designed and disposable unit, equipped with either a standard mercury-in-glass thermometer or any one of a range of commercially available electronic thermometers. Provision is made to collect a urine sample simultaneously if required.

Adult↗