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Biomedical subjects

O Güven

Publications and source records attributed to O Güven.

At least 37 records · Page 2Linked to original sources
PubMed1996

In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-based hydrogels.

In this in vitro study, the biocompatibility of acrylamide-based hydrogels such as acrylamide/crotonic and acrylamide/itaconic acid, prepared by using gamma-rays, has been investigated against some biochemical parameters of human serum. The swelling kinetics of acrylamide/crotonic and acrylamide/itaconic acid hydrogels are investigated in distilled water and physiological saline solution and some swelling and diffusion parameters have been calculated. For the analysis of biocompatibility, acrylamide/crotonic and acrylamide/itaconic acid hydrogels are incubated in 10 different human sera for 24 h and their biocompatibilities with some biochemical parameters have been investigated. No significant difference in values before and after the test procedures have been found. It is therefore concluded that acrylamide/crotonic and acrylamide/itaconic acid hydrogels are biocompatible.

Acrylamide↗
PubMed1996

A biomechanical comparison between original and used titanium miniplates.

Four dogs were chosen for this study. An experimental fracture was made in the mandibular symphysis region of each dog. Two miniplates and eight screws were applied, and removed three and six months postoperatively. In this study, the surface and mechanical characteristics of titanium miniplates were evaluated. Study materials consisted of four groups. In each of the groups, there were six miniplates. The groups are as follows: Group A: Original plates (not used) as a control (i.e. used as a reference in comparisons) Group B: Original plates bent as in operation but not left in tissue Group C: Plates removed at third month postoperatively Group D: Plates removed at sixth month postoperatively. After evaluation of all groups, there was no difference in the microstructure of the surfaces but some differences in mechanical characteristics were apparent.

Animals↗
PubMed1995

Pulpal and apical changes secondary to segmental osteotomy in the mandible--an experimental study.

Posterior segmental osteotomies were performed on 7 dogs to investigate postoperative changes in the pulpal and periodontal tissue. Osteotomy cuts were made at various distances from the apices of roots. After 3 to 6 months, results were evaluated clinically, radiographically and histopathologically. Clinical and radiographic healing of the osteotomy sites was uneventful. Histological evaluation revealed that when the osteotomy cuts were made at a safe distance (3-5 mm) from the apices of roots, neither important pulpal degeneration nor loss of teeth occurred. Even two of the teeth whose apices were cut off had completely healthy pulpal and periapical tissues. The periodontium in almost all of the cases was also found to be healthy.

Animals↗
PubMed1995

Reversible anterior cord syndrome due to penetration of the spinal canal by pedicular screws.

The use of transpedicular screws in patients with disturbed posterior column anatomy is sometimes hazardous. We report a patient with a burst fracture at T7 who developed an anterior cord syndrome immediately after posterior instrumentation. Diagnosis of the anterior cord syndrome was ascertained by an emergency computerised tomogram which showed a misplaced screw compressing the cord from the anterolateral aspect of the spinal canal. Extraction of this screw and revision of the instrumentation resulted in speedy and complete resolution of the neurological deficit. The patient was mobilised within the first postoperative week and was able to work by the fourth postoperative month. The application of smooth contoured screws and blunt surgical instruments was found to be helpful because they are less likely to produce a cutting injury of neural tissue. We must further stress that transpedicular screws for the upper thoracic segments are to be employed very cautiously, if ever, to avoid severe neurological complications.

Adult↗
PubMed1995

Transpedicular drainage of Pott's abscess. A report of two cases.

The treatment of Pott's disease remains controversial. The authors present two cases of spinal tuberculosis treated with posterior stabilization and supplementary abscess evacuation via the pedicular route with subsequent chemotherapy. The aim of this procedure was to increase the healing rate. Radiographic evidence of bone healing without any sequelae was demonstrated at 13 and 14 months.

Abscess↗
PubMed1994

A single stage posterior approach and rigid fixation for preventing kyphosis in the treatment of spinal tuberculosis.

STUDY DESIGN: The authors employed a new mode of treatment for spinal tuberculosis consisting of single stage posterior instrumentation and fusion without anterior debridement. Ten patients were operated upon in this manner. Chemotherapy was instituted 2 weeks preoperatively and continued for a mean period of 11 months. Cotrel-Dubousset or a comparable system was used for fixation. OBJECTIVES: Patients were followed for 3 monthly intervals with serial anteroposterior and lateral x-rays, erythrocyte sedimentation rate, physical examination, and patients' self reports. The mean follow up period was 24.2 months (range, 17-36 months). METHODS: Measurement of kyphosis angle in the lateral x-ray view was used to evaluate treatment. RESULTS: Only a 3.4 degrees mean loss of correction was observed over the follow-up period. All patients were satisfied. CONCLUSION: Our results show that posterior rigid fixation and chemotherapy provide satisfactory stabilization, reduce surgical morbidity, and prevent development of late kyphosis in selected patients with Pott's disease of the thoracolumbar spine.

Antitubercular Agents↗
PubMed1994

Adsorption of bovine serum albumin onto acrylamide-maleic acid hydrogels.

In this study, acrylamide-maleic acid hydrogels containing different amounts of maleic acid have been prepared by irradiating with gamma radiation. They have been used in experiments on bovine serum albumin (BSA) adsorption. Acrylamide-maleic acid hydrogel containing 60 mg of maleic acid and irradiated at 5.20 kGy has been used for swelling and diffusion studies in water, solutions of NaCl and BSA. For this hydrogel, maximum and minimum swellings have been observed with water (1680%) and the solution of BSA (1085%), respectively. Diffusions of water, NaCl and BSA within hydrogels have been found as non-Fickian types of diffusion. In the experiments of BSA adsorption, Langmuir type adsorption has been found. The hydrogel prepared with 60 mg maleic acid and having been irradiated at 2.00 kGy has been found to be the best adsorption system for BSA. The adsorption capacity of acrylamide hydrogel has been increased by the addition of maleic acid almost 1.5-3-fold.

Acrylic Resins↗
PubMed1994

Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets.

Buccoadhesive controlled-release systems for the delivery of morphine sulfate were prepared by compression of hydroxypropyl methylcellulose (HPMC) with carbomer (CP), which served as the bioactive adhesive compound. The release behavior of systems containing 30 mg of morphine sulfate and various amounts of the two polymers was found to be non-Fickian. The adhesion force was significantly affected by the mixing ratio of HPMC and CP in the tablet, and the weakest adhesion force was observed at a ratio of 1:1 (HPMC:CP). Interpolymer complex formation was confirmed between HPMC and CP in acidic medium by turbidity, viscosity, and FT-IR measurements. The amount absorbed (percentage of the drug loaded) of the controlled-release buccoadhesive tablets in six healthy volunteers and was 30 +/- 5%.

Absorption↗
PubMed1994

Concomitant rotator cuff tear and brachial plexus injury in association with anterior shoulder dislocation: unhappy triad of the shoulder.

High incidences of nerve lesions or rotator cuff tears in association with shoulder dislocations have been reported. However, the simultaneous occurrence of these three lesions has only been reported once previously. This case is an example of a not so uncommon injury, which emphasizes the importance of looking for associated brachial plexus and rotator cuff lesions when examining a patient with shoulder dislocation.

Brachial Plexus↗
PubMed1994

Postoperative evaluation of transpedicular screws with computed tomography.

The accuracy of screw placement was assessed with postoperative computed tomography (CT) scans in 75 consecutive patients treated with transpedicular screw fixation. The pedicular screws (n = 379) were inserted at levels ranging from thoracal (T-8) to sacral (S-2) vertebrae using different systems. Most of the screws (90%) were correctly placed in the pedicle. Ten screws (3%) were inserted medially into the spinal canal. Only 1 screw caused root compression symptoms. Screw misplacement lateral to the pedicle occurred in 18 cases (5%), 9 screws (2%) were inserted superior to the pedicle. No important complications developed that were related to the misplaced screws.

Adolescent↗
PubMed1990

Maxillofacial fractures related to work accidents.

Work-related maxillofacial fractures were studied retrospectively over a six-year period. There were 98 cases accounting for 4.5% of all facial bone fractures treated in our hospital between 1981 and 1986. Of the patients, 89.8% were male. The mean age of the injured was 36.4 years. The incidence of work-related maxillofacial fractures was 0.37 per 1000 workers. Most of the injuries (66%) occurred in factories and construction work. Such work was associated with an to 15 times higher risk of maxillofacial fracture than service and office work. Of the fractures, 20.4% were sustained on the way to or coming from work. At the place of work, the commonest causes of injury were blows from objects or falls from a height (70%). On the way to or coming from work, the aetiological factor was most often a traffic accident. Assault and battery had caused facial bone fractures in 11.2% of cases. Fifty-five patients with midface and 45 patients with mandibular fractures were found, of these, 8 patients had bimaxillary fractures. In 6 cases, only dentoalveolar fractures were found. Of the patients, 55.1% were treated operatively. Sixty-six patients were hospitalized, the mean length of hospital stay being 3.2 days (range 1-12 days).

Accidents, Occupational↗
PubMed1990

The investigation of serum and salivary, immunoglobulin levels in patients with head and neck region cancer.

Tumor immunology has been studied in animal experiments. The studies of Prehn and Main in the year 1957, have been pioneer studies. The early diagnosis of cancer, the prognosis, proflaksia and treatment has been studied in several immunological experiments and is still being studied. In the investigations being made before the Second World War mostly the Conditions after the immunological answer has been studied from the beginning where the antigen enters the body and which organs and tissues the antigen enters, which cells do recognise and how the immunological answers is formed. By solving the secrets of the immunological system, oto-immunological, allergic diseases and cancer would be able to be treated easier it is possible that much more better results will be able to be reached with organ transformation.

Adult↗
PubMed1990

[Intramuscular hemangioma of the M. massetericus].

Intramuscular hemangiomas are distinct neoplasms originating within normal skeletal muscle. They represent less than I % of all hemangiomas and occur most frequently in the trunk of extremities, perhaps because of the larger muscle volume in these areas. They occasionally occur in the head and neck area and we present an unusual localisation of intramuscular hemangioma; M. Massetericus.

Head and Neck Neoplasms↗
PubMed1989

[Anterior body ostectomy for mandibular prognathism].

The mandibular body ostectomy is indicated for the correction of select cases of; Mandibular prognathism, Class III open-bite deformity, Anterior crossbite in the adult. The anterior body ostectomy is indicated primarily in selected cases of mandibular prognathism, class III malocclusion when the posterior teeth are not in crossbite or the crossbite is dental in nature and can readily be resolved with conventional orthodontics. As with the correction of other dentofacial deformities, carefully done model surgery and a cephalometric prediction tracing are imperative in planning the anterior body ostectomy. In this paper, a case of mandibular prognathism which is corrected by the technique of anterior body ostectomy is presented.

Adult↗
PubMed1989

["Long face" and orthodontic surgery].

The authors suggest a taxonomy and a specific terminology for vertical maxillo/mandibular excess dysmorphies, "Long face" or "High face". They distinguish three anomalies which may, separate or in association, cause an increased vertical dimension of face; a. Hypsomaxillia, b. Hypsogenia, c. Hypsostomy. In this paper a case of "Long face" and its surgical treatment will be presented.

Humans↗
PubMed1988

A comparative study on maxillofacial fractures in central and eastern Anatolia. A retrospective study.

The present report is an analysis of 190 patients with maxillofacial fractures from East Anatolia, and 212 patients with maxillofacial fractures from Central Anatolia. The aetiology, types, sites, sex, age, treatment and the results are discussed. These showed a high male:female ratio. The highest incidence was seen in the second and third decades and the lowest incidence in the seventh decade. The predominant causative factor in this study was traffic accidents, followed by fights and falls. Fractures of the body of the mandible, and LeFort I fractures in the midface, were the most common fractures in this study.

Adolescent↗