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Biomedical subjects

O Gafencu

Publications and source records attributed to O Gafencu.

At least 19 recordsLinked to original sources
PubMed2001

[Ophthalmologic involvement of intracranial tumors--report of a case].

Bilateral papillary edema is considered to be the expression of a tumoral process that reduces the intracranial space resulting in elevation of the intracranial cerebrospinal fluid pressure. The authors present the case of a 21-year-old man consulting for mild visual loss of the left eye. The ophthalmologic examination showed bilateral papilledema and visual field defects in the left eye (enlargement of the blind spot), with no clinic or imagistic signs of increased intracranial pressure. Intracranial pathologic processes that bear like a tumor, reducing the intracranial space are not always associated with papilledema, but papilledema is always associated with intracranial tumor. Increased intracranial pressure is frequently associated with intracranial tumoral processes, but in this case was not showed increasing of intracranial pressure.

Adult↗
PubMed2001

[Surgical principles and techniques in severe proliferative diabetic retinopathy].

The development and new achievements of the last 30 years in vitreo-retinal surgery, since Machemer developed pars plana vitrectomy as surgical treatment of diabetic retinopathy, have led to a marked change of indications as well as surgical techniques which are applied in this disease. Surgical indications in severe proliferative diabetic retinopathy are: severe vitreous hemorrhage, tractional retinal detachment recently involving the macula, combined tractional and regmatogenous retinal detachment, severe fibrovascular proliferation, premacular dense hemorrhage, chronic macular edema, hemolytic glaucoma and anterior segment neovascularization with media opacity.

Diabetic Retinopathy↗
PubMed2000

[Specular microscopy--its clinical implications].

Specular microscopy has multiple advantages in the clinical practice, allowing the study of the corneal endothelium in-vivo. We can observe corneal disorders, as well as the corneal status after intraocular surgery, of the posterior pole as well as of the anterior pole of the eye.

Cataract Extraction↗
PubMed2000

[Optical coherence tomography].

Optical coherence tomography is a novel, noninvasive, noncontact and repetitive imaging technique which produces high depth resolution cross-sectional tomographs of ocular tissue. It's value is given by the possibility of achieving pseudo-histological images of the target tissue. It is optically based, analogue to ultrasound B-scan examination and similar to laser reflectometry. Optical coherence tomography involves shining low-level infrared light on a tissue specimen, an interferometer and a computerized imaging system. The most attractive applications of optical coherence tomography are the diseases of the retina such as: central serous retinopathy, macular hole, chronic macular edema, age-related macular degenerescence.

Diagnostic Techniques, Ophthalmological↗
PubMed2000

[An inclusion cyst of the anterior chamber].

Our paper present a clinical case of inclusion cyst of the anterior chamber. We discuss the clinical course, the specific investigations, the surgical management and the histopathologic diagnosis.

Adult↗
PubMed1999

Topical netilmicin compared with tobramycin in the treatment of external ocular infection.

In a pilot double-blind, randomized, prospective controlled study the effectiveness and safety of 0.3% netilmicin ophthalmic solution were compared with those of 0.3% tobramycin in treating external bacterial ocular infections in 45 eligible patients. The treatment with both study medications resulted in a significant (p < 0.001, Wilcoxon test) reduction in the mean cumulative score of the signs and symptoms. However, no statistically significant differences were observed between the two groups. The clinical improvement rate was almost complete with either antibiotics. There was a statistically positive trend in the netilmicin group with regard to the microbiological improvement that was achieved in (87% of the netilmicin patients) compared with 77% of the tobramycin patients (77%). Antibiotic sensitivity revealed that 84% of the organisms isolated were sensitive to netilmicin whereas only 64% of them were sensitive to tobramycin. Only minor adverse events occurred in patients treated with either netilmicin or tobramycin. In conclusion, this study demonstrates that netilmicin is a promising new antibiotic for treating external ocular infections.

Administration, Topical↗
PubMed1999

[Emergency keratoplasty].

In some ocular diseases may occur the corneal perforation. This condition requires an emergency penetrating keratoplasty. We show in this paper the conditions, surgical techniques and the complications in this kind of surgical intervention, with examples from our clinical cases.

Cornea↗
PubMed1999

[Prostaglandin esters--new directions in the treatment of glaucoma].

The therapeutically approach of glaucoma still represent a problem of the ophthalmology. Latanoprost, a new prostaglandin derivative, fall the intraocular pressure as good in the night as during the day by its special way of action. Since January 1998, in the Eye Clinic of the Central Military Hospital, we studying the ocular hypotensive effects of the latanoprost. Our results seems to confirm the efficacy of this prostaglandin analogue.

Adult↗
PubMed1998

[The anterior segment ischemia syndrome].

Starting from a clinical case, the paper presents a rare complication of the strabismus and retinal detachment surgery: the anterior segment ischemia syndrome. In this context, we discuss the clinical and pathogenetic circumstances of apparition, underlining the great importance of primary prophylaxis.

Anterior Eye Segment↗
PubMed1998

[CMV retinitis--"the lightning that announces a storm"].

After a theoretic presentation, the authors show the results of a study on 11 patients with cytomegalovirus retinitis. We observed the slowing of the evolution of the retinal lesions. Of 11 patients, 8 comes the first time to the physician for ocular symptoms. The CMV retinitis may predict the presence of HIV infection.

AIDS-Related Opportunistic Infections↗
PubMed1998

[Retinopathy of prematurity].

The paper presents theoretical aspects about the pathogenesis, diagnosis and treatment of the retinopathy of prematurity.

Antioxidants↗
PubMed1998

[A giant arterial aneurysm with an inferior paramacular location--a clinical case].

The authors report the case of a 72-year-old patient with a sudden loss of the visual acuity of her unifunctional right eye. The ophthalmoscopy and the angiofluorography of the right eye showed a vascular tumour that is situated paramacular inferior, a long temporal arterial branch. Clinical and biochemical investigations permitted the diagnostic of arterial aneurysm developed on systemic hypertension and vascular fragility of the patient. It is very possible that an occlusive or a spastic downstream component to be at the origin of the aneurysm.

Aged↗
PubMed1998

[HLA antigens and ocular pathology].

The HLA antigen system is a complex of genes which have the control of a lot of cellular receptors with high role in histocompatibility, genes which code the born of all molecules may play a significant role in graft reaction and in starting the immunologic answer. The immunological study was demonstrated that many ophthalmological diseases are very deep linked by the HLA antigens.

Cornea↗
PubMed1997

[Carbonic anhydrase inhibitors with topical action in the treatment of glaucomatous diseases. A preliminary note].

Seven patients with open angle glaucoma were treated using Dorsolamida twice daily together Betablocant treat. Five patients with secondary glaucoma were treated with Dorsolamida three time daily as well three patients with edematous postimplant keratopathy. Intraocular pressure decreased with an average of 3-4 mm Hg and at the patients with corneal edema that decreased.

Administration, Topical↗