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Biomedical subjects

O Graadal

Publications and source records attributed to O Graadal.

11 recordsLinked to original sources
PubMed1994

[Aortoiliac arteriosclerosis treated with bypass surgery].

After introduction of the crimped Dacron bifurcation prosthesis, bypass surgery has been the preferred surgical treatment for arteriosclerosis in the aortoiliacal segment. During the years 1979-88 we performed 152 aortoiliacal/femoral bypass operations. Perioperative mortality was 2%, while 96% of patients experienced improvement from operation. Primary and secondary five-year graft patency rates were 84 and 88%. Considering the high risk in this patient group, we regard the operational mortality to be acceptable, and the long term results satisfactory. However, surgical treatment should be reserved for patients with serious occlusive disease in the aortoiliac segment. For patients with more limited lesions, endovascular procedures are a relevant alternative to surgery.

Adult↗
PubMed1994

[Crohn disease. Long-term effects of surgical treatment].

Surgical treatment of Crohn's disease is an alternative when the symptoms are not adequately relieved by drugs. The initial result of intestinal resection is usually good, but in most cases the disease re-occurs after varying periods of time. The article describes a study of the long-term results of surgical treatment. 58 patients were followed up 10-25 years after surgery. 38% had been re-operated within ten years, and 54% within 15 years. None of the patients had been re-operated more than 15 years after the initial operation. After an average observation time of 18 years, 35% had no symptoms, and 65% had symptoms probably caused by Crohn's disease. Of the 17 patients with no clinical symptoms at follow-up, 11 had been re-operated once or several times. Only six of the patients were symptom-free without reoperation. The authors conclude that, although a permanent cure of Crohn's disease is rarely achieved by surgery, it is a valuable form of treatment for patients with incapacitating symptoms.

Adolescent↗
PubMed1992

[Pseudomembranous colitis. Surgical treatment].

Pseudomembranous colitis is an inflammatory intestinal disease that is usually secondary to antibiotic treatment. The disease upsets the normal bacterial flora of the large intestine. Therapy consists of fluid replacement, discontinuation of broad-spectrum antibiotics and treatment with vancomycin or metronidazole. In severe or resistant cases surgical treatment is required. We describe one case history and give some guidelines for surgical treatment.

Cecum↗
PubMed1990

[Pancreatic cancer. Treatment and results].

Between 1980 and 1989, 151 patients were treated for adenocarcinoma of the pancreas. One fifth of the patients underwent radical surgery whereas 1/3 had a palliative operation. Leakage from the pancreatico-duodenal anastomosis, constructed with a mucosa to mucosa technique, did not occur in patients operated with pancreatico-duodenal resection (n = 19). The postoperative lethality in this group was 5%. Median overall survival time was four months, after a radical operation 11.5 months and after a palliative operation five months. Five patients with cancer of the papillary region had a median survival time of 40 months and four patients are still alive.

Adenocarcinoma↗
PubMed1990

[Use of resources in the treatment of pancreatic cancer].

We calculated the costs of surgery for pancreatic cancer in 151 patients treated for carcinoma of the pancreas at Ullevål sykehus, University of Oslo, during the period 1980-89. The costs of the diagnostic process and the hospital stay were calculated separately. We found that radical surgery cost about NOK 80,000 more than a palliative operation. The median survival time after radical operation was only 11 months, compared with five months after palliative surgery. We are discussing the price of the surgery in relation to the results. We stress the importance of restrictive selection criteria for radical surgery of pancreatic cancer and conclude that the higher cost of radical surgery as compared with palliative procedures is acceptable.

Adult↗
PubMed1990

[Study and diagnosis of pancreatic cancer].

The most common initial symptom was abdominal pain. Other frequent debut symptoms were loss of weight and jaundice. ERCP and PTC were found to be the best diagnostic procedures. CT or ultrasonography were normal in 10-20% of the patients. Nearly all tumors of the pancreas were found by the ERCP procedure. We also used angiography to evaluate operability of the pancreas tumor. Angiography was found to be a very uncertain diagnostic procedure, however, and we have now decided not to use angiography in the future evaluation of patients with cancer of the pancreas.

Adult↗