Different Therapy of Bromisoval Poisoning and Primary Detoxication by Gastrotomy or Duodenotomy: Bromisoval poisoning is encumbered with a high complication rate and mortality. Primary and secondary detoxication methods differ in efficacy and risk of the method. Primary detoxication deserves prefrence because it terminates the invasion of the poison, the duration of coma is shortened and complications due to poisoning are eliminated. An extremely effective, and at the same time involving little risk, primary detoxication can be undertaken by gastrotomy or duodenotomy, because the tablet substances remain visible for a long time as radiopaque conglomerates in the stomach and suprapapillary duodenum. In 5 cases with 30 to 70 g carbamide, the duration of the coma was cut by more than half compared with 25 equally severe poisoning treated in the usual manner.

Adolescent↗

PubMed1977

[The hemolytic uremic syndrome (HUS) as the terminal stage of a generalized vascular disease with Raynaud phenomena. A contribution on the pathogenesis of mesenchymal diseases].

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Adult↗

PubMed1977

[Carbamide detoxication by gastro- and duodenotomy].

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Duodenum↗

PubMed1975

[Bronchial asthma. Pathogenetic assumptions - therapeutic guidelines - the significance of synthetic corticotrophin (ACTH) in its treatment (author's transl)].

The treatment procedure with 121 in-patients suffering from respiratory obstruction is described following a short review of the etiology and pathogenesis of bronchial asthma, and the consequences for treatment resulting therefrom. While patients with chronic bronchitis caused by an emphysema of the lungs were treated primarily with antibiotics, synthetic corticotrophin (Synacthen, Synacthen Depot) and/or cortisone were prescribed in the treatment of 3/4 of the cases involving asthmatics and patients with chronic asthmatoid bronchitis caused by an emphysema. In severe cases ACTH was combined with cortisone. As a result of corticotrophin's direct effect on the bronchial muscles and the mast cells, along with its stimulation of the adrenal cortex, treatment with ACTH has the advantage over the classic cortisone treatment of retaining the functional ability of the adrenal cortex and reducing the amount of cortisone needed. No ACTH-caused side effects were reported. Included are tables containing guidelines for therapy suitable in private practice.

Adrenocorticotropic Hormone↗