Dr. Maude Abbott deserves better.
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Biomedical subjects
Publications and source records attributed to O H Warwick.
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Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity. The neurotoxicity was associated with oculomotor disturbances expressed primarily as weakness of convergence and divergence. Detailed postmortem examination of one patient revealed no anatomical abnormalities of the central nervous system. The ocular motor disturbances are probably an expression of regional 5-FU neurotoxicity primarily affecting the brain stem.
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Information was obtained from 104 of 106 surviving women medical graduates of the University of Western Ontario in a study designed to determine subsequent working careers and related factors. Of those who had graduated six or more years before this study 85% were engaged in medical work (66% full-time and 19% part-time). General practice, psychiatry and preventive medicine were the leading categories of work. Childbearing was the most important determinant of occupational status. Fewer of the women who had borne children were currently engaged in medical work than were either single or childless married women. The apparent contribution of other factors to working status arose from their correlation with child-bearing. Comparison with other studies suggests that the percentage of female graduates doing medical work is substantially higher than in Britain and about the same as in the United States.