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Physician-Patient Relations↗
Biomedical subjects
O Hellström
Publications and source records attributed to O Hellström.
Localized outbreak of enteroviral meningitis in adults.
During a thorough surveillance of viral infections of the central nervous system an outbreak of aseptic meningitis was discovered in the western part of Finland in late 1985. The 21 diseased young adults were carefully studied by different virological methods. A presumed viral etiology, in all cases of enteroviral origin, was found in 16 of 20 (80%) with adequate specimens. Four different enteroviruses were associated with this episode; in 9 cases the presumed etiological agent was echovirus 5, while coxsackie B5, echo 25 and echo 17 viruses appeared to be responsible for 4, 2 and 1 case, respectively. Sensitivity of different diagnostic methods as regards detection of the echovirus 5 infections was in order: increase of type-specific neutralizing serum antibodies, isolation of virus from faeces, isolation from throat and group diagnosis by demonstrating an increase in complement-fixing antibodies to coxsackie B5 virus antigen.
Adult↗
A trial of selenium and vitamin E in boys with muscular dystrophy.
The administration of selenium and vitamin E was tried in a group of 20 boys with muscular dystrophy. Muscular strength was measured at intervals of 6 months. The boys were treated for 1 year (selenium 6 micrograms/kg for 6 months and 20 micrograms/kg for 6 months), followed by 1 year of no treatment. The whole series was completed in 16 boys, nine of whom had classical Duchenne muscular dystrophy and the rest who had more benign variants. No boy showed any side effects. The decrease of muscle strength was slightly more rapid during the second year (no treatment) than during the first year (with treatment) of the trial. The difference was, however, slight and could conceivably be explained by the increase of age. No boy showed any practically usable increase of muscle strength during the year of treatment. The minimal muscle strength required for walking is presented.
Adolescent↗
Muscle strength and balance in post-stroke patients.
Isokinetic torque of the knee and elbow during maximal extension and flexion and isometric strength of the handgrip, as well as balance and some circulatory variables, were tested in 37 patients one year after an acute stroke. Correlations with locomotion, household work and other activities of daily living (ADL) were tested. Male patients who had received special activation on the ward for up to 4 weeks after the stroke showed a significantly smaller difference in strength between the paretic and non-paretic knee at an angular velocity of 90 degrees per second than males who had received only routine activation on their ward. There was a high correlation between locomotion and the isokinetic torque of the paretic knee and also between locomotion and balance. The correlations between elbow strength and ADL functions were weaker. It was concluded that the evaluation of the isokinetic muscle torque of the knee and the balance tests are valid instruments for estimating functional capacity after a stroke.
Activities of Daily Living↗