Biomedical subjects

O I Korneliuk

Publications and source records attributed to O I Korneliuk.

2 recordsLinked to original sources

PubMedDate not supplied

[Microarrays: technologies overview and data analysis].

DNA microarrays are a powerful tool to investigate differential gene expression for thousands of genes simultaneously. In this review, recent advances in DNA microarray technologies and their applications are examined. Various DNA microarray platforms are described along with their methods for fabrication and their use. In addition some algorithms and tools for the analysis of microarray expression data, including clustering methods, partitioning and machine learning methods are discussed.

Gene Expression Profiling↗

PubMedDate not supplied

[Tyrosine tRNA(Q*psiA) from bovine liver. Identification of its sites of interaction with homologous aminoacyl-trna synthetase using chemical modification].

Interaction of the bovine liver tyrosine tRNA Q*psi A having short variable loop, with the homologous aminoacyl-tRNA synthetase has been studied by alkylation with ethylnitrosourea. It is shown that tyrosyl-tRNA synthetase (form M.r. 2x39000) protects 3'-phosphates of nucleotides 21 in D-loop, 31 and 44 in anticodon stem and 59-64 T psi C-stem of tRNA Tyr from alkylation. An anticodon of tRNA Tyr did not interact with this proteolytically modified form of tyrosyl-tRNA synthetase (M.r. 2x39000).

Amino Acyl-tRNA Synthetases↗