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Biomedical subjects

O I Pikuza

Publications and source records attributed to O I Pikuza.

11 recordsLinked to original sources

[Medium-weight molecules and their indicator role in young children with acute pneumonia].

As many as 63 infants with acute pneumonia, 7 children with ARVI (bronchiolitis) and 28 normal children were examined. At the height of the clinical manifestations there was an increase of the level of medium-weight molecules in blood serum, correlating well with the disease gravity determined by the intensity of the toxic syndrome. The highest concentration of serum medium-weight molecules was demonstrable in toxic and purulent complications due to acute pneumonia. Meanwhile the level of medium-weight molecules, equal to or exceeding 0.6 Units extinction may be viewed as an unfavourable predictor. No relationship was discovered between the concentration of serum medium-weight molecules and the type of virus causative agent and respiratory tract inflammation.

Acute Disease↗

[The characteristics of the humoral antibacterial immunity of young children with respiratory organ diseases].

The state of antibacterial humoral immunity in young children with acute bronchitis, acute obstructive bronchitis and bronchial asthma at the period of exacerbation has been shown with the use of the enzyme immunoassay. The concentration of antibodies to endotoxin positively correlates with the severity of clinical manifestations of the endogenic intoxication of the body. As the inflammatory process in the bronchial tree increases, the spectrum bacterial agents to which elevated concentrations of specific antibodies can be detected becomes wider, and this finds its maximum reflection in bronchial asthma.

Acute Disease↗