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Biomedical subjects

O K Golubchenko

Publications and source records attributed to O K Golubchenko.

15 recordsLinked to original sources

[The possibility for the intravital diagnosis of a dissecting aortic aneurysm].

On the basis of experience gained in vital diagnosis of dissecting aneurysm, its thoracic portion, in 3 patients the authors note that accurate diagnosis of this pathology cannot be made without analysis of a complex of diagnostic studies that rely on a correct assessment of clinical manifestations of the disease. The following items should be noted: particular features of the pain syndrome, migration of the pain zone and relapsing character of pain; lack of a clear-cut interrelation between intensity and duration of pain and frequency of development of cardiogenic shock and cardial asthma; correlation between changes in blood count (leukocytosis) and blood levels of transaminases; absence of the typical ECG features of myocardial infarction, and character of time-related changes.

Aortic Dissection↗

[Evaluation of diagnostic indices of reactivity during treatment of patients with chronic bronchitis and bronchiectatic disease].

Evaluation of neutrophils conditions by glycogen, enzymatic activity (acid and alkaline phosphatases, peroxidase), lymphocyte blast-transformation reaction stimulated by staphylococcal antigen in 113 patients with bronchial pathology on treatment suggested the conclusion of their value in verification of the disease course correction of on-going treatment and definition of its effect. The methods acquire additional significance in objective assessment of the process activity in obscure clinical manifestations and lack of laboratory evidence for aggravation.

Bronchiectasis↗

[The immunological reactivity indices of patients with chronic nonspecific lung diseases].

At height of the disease patients with chronic bronchitis showed a reduction of immunological indices of reactivity of the body. A direct dependence was established between the severity of the course of the disease and degree of reactivity reduction. Absence of complete normalization of indices of immunological reactivity at discharge from the clinic indicates incomplete control of the inflammatory process and short-term character of the remission. The reaction of lymphocyte blast transformation may be used for detection of both latent and clinically manifest staphylococcal infection. Increased sensitivity to staphylococcal allergen results in a reduction of the phagocytic activity of neutrophils in patients with chronic bronchitis.

Antigen-Antibody Reactions↗