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O K Ndimbie

Publications and source records attributed to O K Ndimbie.

3 recordsLinked to original sources

Hemangiomas with localized nodular proliferation of the liver. A suggestion on the pathogenesis of focal nodular hyperplasia.

Multiple cavernous hemangiomas circumscribed by focal regenerative nodules of hepatocytes were incidental findings at the autopsy of two elderly men. Neither patient was on steroids or had venous thrombosis. The lesions were not typical for other nodular proliferations of the liver, such as focal nodular hyperplasia, nodular regenerative hyperplasia, or liver cell adenoma, and they have not been previously reported. We also explore the roles of vascular malformation, oral contraceptives, and thrombosis in the pathogenesis of localized nodular proliferation of the liver.

Aged

Lupus anticoagulant associated with specific inhibition of factor VII in a patient with AIDS.

A 37-year-old intravenous drug abuser with acquired immune deficiency syndrome showed elevated activated partial thromboplastin time (APTT) and prothrombin time, normal thrombin time and fibrinogen, and borderline low platelet counts. The patient subsequently had a fracture of the left zygomatic arch, which did not produce uncontrollable bleeding. The coagulogram repeated at this admission showed persistent elevation of APTT. Further coagulation workup showed the presence of a lupus anticoagulant with mild specific inhibition of Factor VII. Platelet aggregation and Factor II levels were normal.

Acquired Immunodeficiency Syndrome

Dendriform pulmonary ossification.

Dendriform pulmonary ossification is a rare entity associated with chronic lung disease that is almost invariably discovered as an incidental finding at autopsy. Antemortem chest roentgenograms of patients with dendriform pulmonary ossification are often interpreted as pulmonary fibrosis and/or bronchiectasis. Radiographic and pathologic findings in two cases are described herein.

Aged