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Biomedical subjects

O Käser

Publications and source records attributed to O Käser.

At least 19 recordsLinked to original sources
PubMed1989

[Development of radical surgical technics in gynecology exemplified by ovarian and cervix cancer].

Surgical treatment of genital cancers has changed over the last 40 to 50 years, as shown by two examples: cancer of the ovary, and cancer of the cervix. With the first, optimal (radical) debulking surgery is the cornerstone of treatment, with the second, a more individualized therapy, including pelvic evisceration for specific indications, are (almost) a generally accepted policy. Controversial issues are the therapeutic effect of an extended aortopelvic lymphadenectomy in both malignancies or the radical parametrial excision in cancer of the cervix. A rather sceptical attitude is taken towards the second-look laparotomy or secondary debulking surgery in cancer of the ovary and the pretherapeutic or staging laparotomy in cervical malignancies.

Female↗
PubMed1986

[Surgical therapy in recurrences and the therapeutic sequelae].

Treatment complications of cancer of the cervix necessitating surgery--bowel obstruction, dead loop syndrome, stenosis or fistulae of the IT or UT--are infrequent. Indications, technique and complications are discussed. Persistent or recurrent cervical cancers in many cases are limited to the pelvis thus offering a chance of surgical cure. Indications, techniques and complications of these extensive operations are dealt with.

Combined Modality Therapy↗
PubMed1984

Cancer of the endometrium stage I--standardized or individualized treatment?

Cancer of the endometrium is the most frequent gynecological cancer in many western countries. About 75% are in stage I, which comprises a wide range of tumors of different prognosis. Survival rates with any form of standardized treatment have not increased significantly in the last decades. The rationale for an individualized treatment of stage I cancers is explained and our present treatment modalities are described. It is for the future to decide whether or not such a policy is beneficial.

Castration↗
PubMed1983

[History of contraception and a look to the future].

The desire to limit procreation is as old as mankind. The means to reduce the number of children has been abortion and infanticide rather than contraception. But contraceptive methods have been used already in prehistoric times. They were partly logical, partly illogical and ineffective. Definite improvements were made in 19th century and a more scientific approach began in the 20th century. In order to master the problems of population explosion in developing countries intensive financial and organizational efforts have to be made.

Christianity↗
PubMed1981

[Topical problems and trends in surgical gynaecology (author's transl)].

Surgical gynaecology in the late seventies was characterised by low lethality but still high morbidity. Comparative studies have remained to be somewhat difficult to undertake for the absence of one coherent, generally accepted definition and listing of intrasurgical and postsurgical complications. Several prophylactic steps are discussed, before reference is made to the choice of a surgical technique by which to cope with benign and malignant diseases. With low lethality and comparable morbidity, consideration may be given to other aspects, as well, including preservation of functionality, prevention of recurrence, and cosmetic requirements. The trend for malignant diseases, today, is to undertake surgery, as conservative as possible and as radical as necessary.

Female↗
PubMed1980

Prevention of postoperative thromboembolism by dextran 70 or low-dose heparin.

The efficacy of intravenous infusion of dextran 70 or subcutaneous administration of low-dose heparin in preventing postoperative thromboembolic complications has been investigated in a prospective randomized trial. During part 1 of the study, 232 patients over the age of 40 years who were undergoing major gynecologic surgery underwent a complete test protocol. The 125I fibrinogen uptake test (FUT) was used for the diagnosis of deep vein thrombosis (DVT) in 117 patients in the dextran and 115 patients in the heparin group. Heparin was significantly more effective than dextran for reducing DVT (P less than .001). During part 2 of the study no FUT was done but the incidence of clinical and fatal pulmonary embolism (PE) and the number of complications were studied. Of 444 patients (parts 1 and 2) 1 fatal and 2 nonfatal pulmonary emboli were diagnosed. All the emboli occurred in the dextran group. The benefit: hazard ratio appeared to favor heparin for the prophylaxis of DVT.

Adult↗