PubMed HealthSearch

Biomedical subjects

O Korhonen

Publications and source records attributed to O Korhonen.

At least 19 recordsLinked to original sources

Thermoregulation during rest and exercise in the cold in pre- and early pubescent boys and in young men.

Eight minimally dressed pre- and early pubescent boys (age 11-12 yr) and 11 young adult men (age 19-34 yr) rested for 20 min and exercised on a cycle ergometer for 40 min at approximately 30% of their maximum oxygen consumption (VO2max) at 5 degrees C. To quantify the added increase in metabolic rate because of cold, a separate test was carried out at 21 degrees C at rest and at equal work rates as in the cold. Both groups were similar in subcutaneous fat thickness and VO2max per kilogram body weight. Rectal temperature increased slightly during the exposure to the cold, but no significant difference was observed between the boys and men. In the cold, the boys had lower skin temperatures than the adults in their extremities but not in the trunk. The boys increased their metabolic rates in the cold more than did the men. As a result, the boys maintained their core temperature as effectively as the adults. Similar age-related differences in thermoregulatory responses to cold were observed when two boys and two men with equal body sizes were compared. Our results suggest that there may be maturation-related differences in thermoregulation in the cold between children and adults.

Adult

An evaluation of heat stress indices (ISO 7243, ISO/DIS 7933) in the prediction of heat strain in unacclimated men.

The ISO 7243 heat stress standard based on the wet bulb globe temperature (WBGT) heat stress index and the analytical standard proposal ISO/DIS 7933 were evaluated in eight physically trained and eight untrained, unacclimated men during prolonged light exercise carried out while wearing industrial work clothing. The exercise tests were done in a thermoneutral (20 degrees C/40%), a warm humid (30 degrees C/80% humidity), and a hot dry (40 degrees C/20% humidity) environment. Both of the standards were effective in predicting the excessive thermal strain observed in the dry and humid heat (WBGT, 28 degrees C). In dry heat, neither of the standards took into account the higher sweating capacities of the physically trained men. The large inter-individual variability in the physiological responses to heat stress questioned the calculations of definite allowable exposure times (ISO/DIS 7933).

Acclimatization

Biomechanical evaluation of heavy tool-handling in two age groups of firemen.

The biomechanical load of a rescue-clearing task (lifting a power saw from the floor up to the ceiling level) was evaluated with six older (47 +/- 5 years) and seven younger firemen (32 +/- 2 years). The mean dynamic compressive force at the L5/SI disc was 5998 N for the older subjects and 6392 N for the younger subjects. The peak torques for the back and knee extensions were about equal for the two groups of the subjects. The younger subjects had a significantly higher movement speed in the knee extension than the older subjects (89.1 +/- 25.7 vs. 35.3 +/- 11.5 degrees/s, p less than 0.001). The results showed that lifting a power saw produced a high load on the musculoskeletal system, and that the load was not influenced by age.

Adult

Effect of work load on cutaneous vascular response to exercise.

The purpose of the present study was to examine whether intensity of exercise affects skin blood flow response to exercise. For this purpose, six healthy men cycled, in a random order on different days, for 15 min at 50, 60, 70, 80, and 90% of their maximum oxygen consumption (VO2max) at a room temperature of 25 degrees C. At the end of exercise, esophageal temperature (Tes) averaged 37.4 +/- 0.2, 37.7 +/- 0.2, 37.9 +/- 0.2, 38.6 +/- 0.3, and 38.9 +/- 0.4 degrees C (SE) at the 50, 60, 70, 80, and 90% work loads, respectively. At the two highest work loads, no steady state was observed in Tes. Skin blood flow was estimated by measuring forearm blood flow (FBF) with strain-gauge plethysmography and by laser-Doppler flowmetry on the upper back. Both techniques showed that skin blood flow response to rising Tes was markedly reduced at the 90% work load compared with other work loads. At the end of exercise, FBF averaged 7.5 +/- 1.7, 10.7 +/- 3.1, 9.6 +/- 2.1, 11.3 +/- 2.6, and 5.4 +/- 1.3 (SE) ml.min-1.100 ml-1 (P less than 0.01) at the 50, 60, 70, 80, and 90% VO2max work loads, respectively. The corresponding values for Tes threshold for cutaneous vasodilation (FBF) were 37.42 +/- 0.16, 37.48 +/- 0.13, 37.59 +/- 0.13, 37.79 +/- 0.19, and 38.20 +/- 0.22 degrees C (P less than 0.05) at 50, 60, 70, 80, and 90% VO2max, respectively. In two subjects, no cutaneous vasodilation was observed at the 90% work load.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

Changes in maximal cardiorespiratory capacity among aging municipal employees.

Before and after a four-year follow-up, maximal oxygen consumption (VO2max) was determined for 67 municipal employees (initial age about 51 years). The VO2max (ml.kg-1) decreased 6% among the women and increased 8% among the men, the greatest and smallest change occurring for employees doing mental and physical work, respectively. The men's increase was associated with an increase in leisure-time physical activity. Work content was not associated with the level of VO2max for either gender. After the four years the women's absolute VO2max was about 66% of the men's. There were marked changes in VO2max at the individual level, the most marked decreases being associated with the use of medication in some cases. After the four years the women's VO2max of 63% was insufficient according to current recommendations. Therefore physically demanding jobs are not generally recommended for older women.

Aging

Aerobic capacity among chronic low-back-pain patients.

The role of aerobic capacity (maximal oxygen uptake, VO2max) in connection with chronic low-back pain was assessed in a study mainly designed to evaluate the outcome of inpatient and outpatient treatment of low-back pain. A total of 245 subjects (ages 35-54 years, 71% men)--81 inpatients, 88 outpatients, and 76 controls--who had chronic low-back pain but who were still working, performed maximal graded bicycle ergometer tests four times during the follow-up of 30 months. In every group the estimated VO2max was on the level of the reference values of healthy persons. There were no significant changes in the VO2max in any of the intervention groups during the follow-up period. The correlation analyses showed no connection between aerobic capacity and pain or disability caused by chronic low-back pain. Among several components of physical fitness, aerobic capacity had no predictive value in the course of low-back pain.

Adult

Responses of young and older men during prolonged exercise in dry and humid heat.

Eight young, sedentary men (aged 34 years, SD 3) and six older moderately active, unacclimated men (aged 57 years, SD 2) walked on a treadmill at 30% of their maximum oxygen consumption up to 3.5 h in a thermoneutral [dry bulb temperature (Td) 21 degrees C, relative humidity (r.h.) 43%)], a warm humid (Tdb 30 degrees C, r.h. 80%) and a hot dry (Tdb 40 degrees C, r.h. 20%) environment while wearing ordinary working clothes (0.7 clo). Their oxygen consumption, heart rate (fc), rectal (Tre) and mean skin temperature (Tsk), sweat rate (SR), and evaporative rate (ER) were measured during the tests. The ratings of thermal sensation (TS) and perceived exertion (RPE) were assessed using standard scales. In the heat stress tests, the number of experiments discontinued did not significantly differ between the two groups. The mean levels and end-exercise values of Tre, Tsk, fc, TS and RPE were not significantly different between the young and older subjects in any of the environments. In the warm humid environment, however, the Tre and RPE of the older subjects increased continuously (P less than 0.05) during the test compared to the young subjects. No significant difference between the groups was observed in SR or in ER. In the hot dry environment, however, the ER of older men increased more slowly compared to the young men. In spite of some time-related differences observed in Tre, RPE, and ER, the older subjects did not exhibit higher fc during exercise in the heat, they were not more hyperthermic and their performance times were similar to the young subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

Vibration perception threshold of forest worker's finger during temporary obstructed blood circulation.

Vibration detection threshold (VPT) of 149 professional forest workers was measured during a compulsory annual health examination. The authors' earlier developed measuring method for VPT of finger was modified. The blood circulation of the hand was obstructed for 6 min and VPT was measured 4 min after releasing the obstruction. VPTs of all forest workers increased during obstruction. In forest workers suffering from decreased hand grip force (decreased HGF) the increase of VPT differed significantly from forest workers without symptoms, and VPT in the former group still increased after releasing the obstruction. VPT remained also at the raised level after releasing the obstruction with forest workers suffering from vibration-induced white finger (VWF). Nevertheless, on an individual basis even the modified measuring method failed to discriminate subjects without symptoms from those with symptoms of hand-arm vibration syndrome. The raised VPT and sensitivity for obstruction of blood circulation suggest that the reason for decreased HGF in forest workers may be a consequence of an injury in the peripheral nerves.

Adult

Measuring method for vibration perception threshold of fingers and its application to vibration exposed workers.

A measuring method for the vibration perception threshold (VPT) of fingers has been developed. The VPTs of 118 and 149 professional forest workers were measured during a compulsory annual health examination in 1979 and 1983, respectively. Also the VPTs of eight pedestal grinders, who were suffering vibration-induced white finger (VWF), were measured in 1979 and 1983. The control group consisted of 20 research workers who had no vibration exposure in the past and no symptoms in their hands. The measuring system for VPT gave repeatable results. The frequency of the most sensitive VPT of vibration exposed workers alternated between 63 and 125 Hz instead of 125 Hz of subjects without vibration exposure. The VPT of the pedestal grinders and forest workers with decreased hand grip force and with vibration-induced white finger were significantly higher than those of the controls. The VPTs of the forest workers decreased slightly and that of the grinders increased from 1979 to 1983. In spite of long vibration exposure in the past and continuing lower level vibration exposure, the increased VPT of forest workers does not seem to be permanent.

Adult

Forestry workers exposed to vibration: a neurological study.

Neurological findings were examined in 186 forestry workers with a mean exposure to chain saw vibration of 16.6 hours. The prevalence of active vibration induced white fingers was 5%, parethaesias of the hands 53%, and muscle weakness 13%. Clinical polyneuropathy was observed in 16 forestry workers in the hands (7.5%) which did not correlate with alcohol consumption. Seventy nine forestry workers of the total population were selected for electromyographic examination. Generalised EMG based polyneuropathy in the hands was observed in only two of the 79 forestry workers (2.5%). The carpal tunnel syndrome was found in 20 of the 79 forestry workers (26%). Headache and vertigo were not linked with exposure to vibration in forestry and a significant part of the numbness reported may be due to the carpal tunnel syndrome. Sensorimotor polyneuropathy is rare among forestry workers. The rise in the vibration detection thresholds was linked to the carpal tunnel syndrome.

Adult

Skin blood flow during incremental exercise in a thermoneutral and a hot dry environment.

Eight physically fit men performed two incremental bicycle ergometer tests, one in an ambient temperature of 25 degrees C and the other at 40 degrees C. Oesophageal temperature (Tes) increased continuously throughout the tests up to 38.0 and 38.3 degrees C, respectively. In both environments, forearm blood flow (plethysmography) was linearly related to Tes above the Tes threshold for vasodilation, but at the heaviest work loads this relationship was clearly attenuated and therefore indicated skin vasoconstriction, which tended to be more pronounced at 25 degrees C. During recovery at 25 degrees C, in some subjects the forearm blood flow increased above the levels observed at the end of the graded exercise in spite of a decreasing Tes. Skin blood flow, measured by laser Doppler flow meter at the shoulder, was quantitatively different but, on average, seemed to reveal the same response pattern as the forearm blood flow. In spite of the higher level of skin blood flow in the heat, blood lactate accumulation did not differ between the two environments. The present results suggest that there is competition between skin vasoconstriction and vasodilation at heavy work rates, the former having precedence in a thermoneutral environment to increase muscle perfusion. During short-term graded exercise in a hot environment, skin vasoconstriction with other circulatory adjustments seems to be able to maintain adequate muscle perfusion at heavy work levels, but probably not during maximum exercise.

Adult

Autonomic neuropathy and vibration exposure in forestry workers.

The variation in heart rate (HRV) at rest and during deep breathing (6 cycles a minute) of 88 professional lumber jacks was studied using a computer technique. The traditional indexes of HRV (CV, CVS, MEAN) were calculated and the spectral components of the HRV were also computed. There was a significant difference (p less than 0.001) between the HRV indexes during the deep breathing test in those with the shortest (CV = 10.1 +/- 1.1) and those with the longest (CV V 6.2 +/- 0.4) exposures to vibration. The values of the HRV indexes decreased with age, but multiple regression analysis showed that the total exposure time to vibration had an independent negative association with the HRV. There were significant differences in all the frequency bands (frequency related power, FRP) of the heart rate between those with the longest and those with the shortest exposures. The HRV during a deep breathing test is associated with the activity of the parasympathetic nervous system and is decreased in autonomic neuropathies. Our results suggest that prolonged exposure to the vibration caused by a chain saw has a negative effect on the parasympathetic activity and thus causes autonomic dysfunction.

Adult

Circulatory and thermal responses of men with different training status to prolonged physical work in dry and humid heat.

Eight physically trained and eight untrained, unacclimated men walked on a treadmill at 30% of their maximum oxygen consumption up to 3.5 h in a thermoneutral [20 degrees C/40% relative humidity (RH)], a warm humid (30 degrees C/80% RH), and a hot dry (40 degrees C/20% RH) environment while wearing industrial work clothing. Their oxygen consumption, rectal and skin temperatures, sweating, cardiac output, heart rate, stroke volume, and peripheral blood pressure were measured during the tests. Thirteen of the 32 heat stress tests were prematurely stopped due to high rectal temperature, high heart rate, subjective fatigue, or heat syncope. The physiological strain, as indicated by the rectal temperature and heart rate, was not significantly different between the warm humid and hot dry environments (wet bulb globe temperature approximately 28 degrees C). The rectal temperature and heart rate responses of the physically trained and untrained subjects did not differ in any of the environments. In the heat, the heart rate was significantly higher than in the thermoneutral environment, but because of the markedly reduced stroke volume the average cardiac output was not different between the three environments. The impaired work performance in the heat seemed mainly to be related to the circulatory instability accompanying the increased cutaneous circulation.

Adult

Effect of indoor feeding season for cattle on lung function of dairy farmers.

The effect of the indoor feeding season for cattle on pulmonary function was studied in 91 randomly selected healthy, non-smoking dairy farmers who did not use personal dust respirators. All the farmers lived in the rural municipality of Pielavesi in eastern Finland. The reference group consisted of 90 healthy, non-smoking urban dwellers who were teachers randomly selected from all the teachers employed by the city of Kuopio (situated in the same administrative district as Pielavesi). Studies of pulmonary function included flow-volume spirometry and measurement of pulmonary diffusing capacity. Among farmers, even a follow-up period of only 6 months was long enough to reveal restrictive impairment in lung function; among teachers restrictive impairment was not found. No evidence of impairment of pulmonary diffusing capacity was found in either of the study groups during the follow-up. Among teachers, changes in lung function did not differ from those previously reported as physiologically normal.

Adult

Methodological aspects of lung function studies.

With several variables, such as patient or subject, disease, surroundings, machine and personnel, it is a wonder that successful epidemiological studies using lung function parameters can be done at all.

Calibration

Hand-grip force in lumberjacks: two-year follow-up.

Hand-grip force was measured in 63 professional lumberjacks in 1978 and again in 1980. Lumberjacks with vibration-induced white fingers (VWF) had lost 21% of their muscle force during the two years. Lumberjacks with no hand-arm symptoms had lost 5% of their muscle force in the same time period. Lumberjacks with subjectively diminished hand muscle force had a slight increase in muscle force during the follow-up time. These results suggest that long-term exposure to vibration causes a decrease in muscle force.

Adult

Effects of industrial respirators on breathing pattern at different work levels.

The effects of a filtering device and an air-line apparatus on breathing pattern were studied in healthy men with different physical characteristics and work capacity. The subjects comprised nine construction workers aged 35-44, and nine firemen aged 21-35. The construction workers' mean maximal oxygen consumption (VO2max) was 34.5 ml min-1 kg-1, the firemen's 66.9 ml min-1 kg-1. Breathing pattern was analyzed for its components, inspiratory time, expiratory time, breathing frequency, tidal volume, and pulmonary ventilation at rest, during two submaximal treadmill walks when the subjects' absolute work load was equal, and during recovery. Neither the filtering device nor the air-line apparatus had a significant effect on breathing pattern when compared with the control values measured twice with a low-resistance breathing valve. A significantly longer expiratory time, lower breathing frequency, and smaller pulmonary ventilation were found for the firemen with the breathing valve and the industrial respirators. The breathing pattern of the construction workers and the firemen differed, but the alterations were not induced by the use of the filtering device or the air-line apparatus when studied at aerobic work levels up to 60% VO2max.

Adult