Biomedical subjects

O Krüger

Publications and source records attributed to O Krüger.

13 recordsLinked to original sources

PubMed1992

[Risk factors and mortality of myocardial infarction in Kristiansund, Alesund and Molde].

We have examined mortality from ischaemic heart disease, prevalence of self-reported coronary heart disease and risk factor levels in three towns (Kristiansund, Alesund and Molde) in the county of Møre og Romsdal. The results for mortality were based on vital statistics for the age group 40-69 years, for the periods 1966-76 and 1977-87. Risk factor data and data on self-reported coronary heart disease for the age groups 40-42 years and 65-67 years were obtained from a health screening survey conducted in the county in 1990. According to the official statistics, the towns share important socio-economic characteristics, but Kristiansund is thought to have stronger roots in the coastal culture, with a historically economic basis in fishery and shipbuilding. We observed substantial differences between the three towns, both as regards risk factor levels and mortality from ischaemic heart disease. By far the highest mortality rates were found in Kristiansund, both for men and for women. A similar gradient existed for the levels of main risk factors, including serum cholesterol, systolic blood pressure and prevalence of smokers. We discuss the implications of these findings for prevention strategies.

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PubMed1991

[Cardiovascular screenings in Norwegian counties. Background and implementation. Status of risk pattern during the period 1986-90 among persons aged 40-42 years in 14 counties].

Screening for cardiovascular disease risk factors was carried out in 14 of Norway's 19 counties in 1986-1990 as part of a prevention programme. All residents aged 40-42 were invited. The attendance was 73.5% for males and 82.6% for females. A total of 87,761 persons were examined. The screening included determination of serum cholesterol and triglycerides, measurement of blood pressure, height and weight, and filling in a questionnaire. Mean serum cholesterol was 5.90 mmol/l for males and 5.55 mmol/l for females, mean systolic blood pressure 135.3 and 126.1 mm, and prevalence of daily smoking 43.5 and 41.8%. The risk factor levels in the 341 municipalities of the 14 counties are shown cartographically. For both sexes, the highest risk score was found in the northernmost county, the lowest in southern counties. The risk was also relatively high in some rural areas in southern Norway. By geographical area there was a strong correlation between the risk factor levels of the two sexes, and a less consistent but marked correlation between the means for the various risk factors.

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PubMed1991

Risk factor changes and mortality changes: a regional perspective on ischaemic heart disease in Norway 1966-85.

This study from Oppland county, Norway, examines risk factor changes in three regions with different mortality time trends among middle-aged males, for ischaemic heart disease, including sudden, unexpected death (IHD/SUD). The study is partly based on vital statistics and on results from two health screening surveys conducted in 1976-78 and in 1981-83. Regional data for the following risk factors are considered: serum cholesterol, systolic blood pressure, body weight and prevalence of smoking. Risk factor data are from the group of men aged 40-49 years in 1976-78. Changes in risk factor levels from 1976-78 to 1981-83 did not differ substantially between regions with widely different mortality time trends. The north-western, rural part of Oppland county experienced 80% IHD/SUD-mortality increase (95% confidence interval 35%-124%) from 1966-70 to 1981-85, among males aged 40-59. The mean serum cholesterol level dropped by 1.7% (P less than 0.001) from 1976-78 to 1981-83, and the prevalence of smoking was also reduced in this region. The north-western rural region experienced a slightly more pronounced increase in mean body weight and in mean systolic blood pressure, compared to the remaining two regions of Oppland county, where the changes in IHD/SUD mortality were not statistically significant. This study has demonstrated that changes in main risk factors are not necessarily accompanied by contemporary IHD/SUD-mortality changes in the same direction. The explanation could be long time-lags before risk factors affect mortality levels. The results could also indicate the presence of other important risk factors, not evenly distributed between the regions.

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PubMed1990

[Myocardial infarction mortality among men 30-69 years of age in Norwegian counties 1966-87].

The article describes mortality from ischaemic heart disease, including sudden, unexpected death, among males aged 30-69 years in all 19 Norwegian counties for the period 1966-87. During this period, the age-adjusted mortality rate in Norway for the 30-69 year age group was highest in 1966-70, and declined by 15% until 1983-87. The decline in mortality was greatest in the 40-49 year age group, but was also clearly evident in the 50-59 and 60-69 year groups. In twelve of the counties there was a statistically significant (p less than 0.05) decrease in mortality from 1966-70 to 1983-87. In one county, Oppland, located in central south-eastern Norway, mortality increased by 19% (p less than 0.01). The increased mortality in this county was most prominent in the 50-59 year group (34%, p less than 0.01). The most favourable change in mortality took place in Rogaland, in south-western Norway, where mortality decreased by 29% (p less than 0.001) from 1966-70 to 1983-87. Positive changes in mortality were also seen in Finnmark, a county with traditionally very high mortality rates. This study was not designed to explain the regional differences in mortality, but the authors point to principal explanatory factors. The regional differences in mortality time trends might be an argument for geographical differentiation of preventive measures.

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PubMed1990

[Mapping of mortality data--ischemic heart disease among men in Norway 1966-87].

We have illustrated how cartography can be used in the study of regional mortality. We chose as an example ischaemic heart disease among males aged 30-69 in Norway during the period 1966-87. Choropleth maps (area shading) and circle maps were used to demonstrate regional differences both as regards level of mortality and mortality time trends. A probability map was produced to show the degree of statistical significance for deviation from the national mortality rate. The examples in this study revealed some regional mortality patterns not previously reported. We conclude that mapping is a valuable method in the study of vital statistics

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PubMed1990

Ischaemic heart disease among men in Norway during the period 1966-1985: two counties with different mortality time trends.

We have examined regional differences in mortality from ischaemic heart disease, including sudden, unexpected death (IHD/SUD), among Norwegian men aged 30-69 years, during the period 1966-1985. Mortality time trends were considered. The two counties with the most widely differing IHD/SUD mortality time trends were Rogaland and Oppland. Rogaland, located in south-western Norway, experienced a 24.1% IHD/SUD mortality rate decrease between 1966-1970 and 1981-1985, while Oppland, in central south-eastern Norway, experienced a mortality rate increase of 12.4%. Marked regional differences within these counties were found. The highest IHD/SUD mortality rate increase occurred in rural areas of Oppland. Urban areas of Rogaland had sharply decreasing rates. Knowledge of such regional mortality differences could provide useful information regarding aetiological factors and serve as a basis for preventive measures and health-care planning.

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PubMed1979