PubMed Health⌕ Search

Biomedical subjects

O Lanczik

Publications and source records attributed to O Lanczik.

8 recordsLinked to original sources
PubMed2006

[Asymptomatic carotid stenoses. Course and discussion of their treatment].

Asymptomatic carotid stenoses are common. They are associated with the risk factors for arteriosclerosis and are a specific risk factor for coronary artery disease, with an annual morbidity/mortality (MM) rate of 8-10%. Detection of a carotid stenosis should therefore be followed by a complete risk factor analysis and modification, if appropriate; a thorough cardiological diagnostic investigation is particularly important. Individual risk indicators for stroke (annual MM 1-2%) are a rapid progression of the degree of stenosis, certain morphological patterns and the presence of extra- and intracranial multi-vessel disease. Trials available so far on the treatment of asymptomatic carotid stenosis have not revealed any significant parameters that would justify individual decisions on whether or not surgery is appropriate. There is therefore a danger that many patients will be exposed to a severe risk of stroke, which cannot be justified unless the centres where such interventions are performed have proven MM complication rates of <3%, the life expectancy of the patients treated is not restricted as the result of other illnesses and the patients explicitly request surgery after a thorough explanation of the risks. Conservative treatment strategies provide the best protection for the majority of patients.

Carotid Stenosis↗
PubMed2005

IV thrombolysis in patients with acute stroke due to spontaneous carotid dissection.

The authors reviewed the histories of 33 patients (ages 44 to 50 years) treated with IV thrombolysis for acute stroke due to spontaneous cervical carotid artery dissection. Median NIH Stroke Scale (NIHSS) score on admission was 15. No new or worsened local signs, subarachnoid hemorrhage, pseudoaneurysm formation, or rupture of the cervical ICA were observed. At 3 months, median NIHSS was 7 and median modified Rankin Scale (mRS) 2.5; mRS < or = 2 was observed in 17 patients.

Adult↗
PubMed2004

[Atypical encephalitis in a 20-year-old soldier].

We report a patient with encephalitis who had been diagnosed with an unspecific aetiology. During follow-up, pneumonia was identified due to Mycoplasma pneumoniae infection that could also be confirmed as causal for the brain inflammation. Despite the initially critical clinical situation, the patient's condition improved under specific antibiotic treatment. Pathophysiologic, differential diagnostic, and therapeutic implications are discussed, and guidelines for diagnosis are proposed.

Adult↗
PubMed2003

Bilateral internal carotid artery dissection mimicking inflammatory demyelinating disease.

BACKGROUND AND PURPOSE: Internal carotid artery (ICA) dissection (ICAD) may be extremely difficult to diagnose only on the basis of historical information and clinical signs, and even standard brain imaging (computed tomography [CT], T2-weighted magnetic resonance imaging [MRI]) may not be sufficient to delineate the underlying pathology clearly, as shown in this case. METHODS: The clinical presentation and parenchymal lesion pattern on CT were suggestive of inflammatory demyelinating disease, and additional multiparametric MRI was performed. RESULTS: Diffusion-weighted MRI, magnetic resonance angiography, and perfusion-weighted MRI revealed acute ischemic lesions, bilateral ICA obstruction, and bilateral hypoperfusion in the middle cerebral artery territories. Bilateral ICAD was confirmed by Doppler and duplex ultrasound, and anticoagulation therapy was initiated. A follow-up examination showed recanalization of the obstructed ICAs and the normalization of cerebral perfusion. CONCLUSION: This case illustrates the importance of demonstrating the pathology and the value of multiparametric MRI techniques for the diagnosis and monitoring of ICAD and its hemodynamic consequences.

Carotid Artery, Internal, Dissection↗