Biomedical subjects

O Latifoglu

Publications and source records attributed to O Latifoglu.

4 recordsLinked to original sources

PubMed2000

Assessment of muscle flap sensibility by evoked potentials in the rat.

This study investigated whether the sensory-to-motor reinervation of the muscle flap provides a better sensory recovery of an overlying skin graft. Fifty-four animals were studied in three groups of 18 rats each: group I (control): 1 cm of the gastrocnemius muscle motor nerve was excised and no repair was performed; group II (motor-to-motor repair): the motor nerve of the gastrocnemius flap was transected and repaired; group III (sensory-to-motor repair): the motor nerve of the gastrocnemius muscle and sural nerve were transected and their distal and proximal ends, respectively, were repaired. At follow-up periods of 6, 12, and 24 weeks, evaluation of hair growth, muscle atrophy, and sensory evoked potentials was performed. Somatosensory evoked potentials (SSEP) at 6 weeks in the sensory-to-motor repair (group III) revealed a significant (P < 0. 05) increase (104.4% +/- 22.9) in the relative response of peak-to-peak potentials when compared with group I (46.6% +/- 19) and group II (51.8% +/- 14.0). Muscle flap stimulation was most prominent at 6 weeks in sensory-to-motor reinvervated flaps (group III 133.1% +/- 25.4; group I 84.9% +/- 20.2). In this study, sensory-to-motor nerve repair significantly improved the sensibility of skin flaps at 6 weeks. Denervated flaps presented with 3 months of sensory recovery delay.

Animals↗

PubMed1998

Combined chemical peeling and dermabrasion for deep acne and posttraumatic scars as well as aging face.

The combination of chemical peeling and dermabrasion for the improvement of facial wrinkles, acne, posttraumatic scars, and abnormal pigmentation was first described by Dupont in 1972 and Horton in 1984. We have been using the combined technique since 1972, and we have obtained more satisfying results than by using these techniques independently. The purpose of this paper is to summarize the results obtained using the combined technique of chemical peeling and dermabrasion and to emphasize a simple method of postoperative care that can be applied after any physical or chemical rejuvenation technique. Whereas the combined technique takes advantage of depth-controlled surgery, less bleeding, less postoperative pain, less risk of local and systemic complications, and longer lasting results, the covering of the wound with one layer of fine mesh gauze is another advantage that provides easy postoperative care.

Acne Vulgaris↗

PubMed1997

Triplicated thumb.

A polydactyly anomaly of the thumb with three nails, two metacarpals, and seven phalanges is presented. This anomaly is named triplicated thumb, and its place in Wassel's classification is discussed. The patient was treated according to the principles of surgery of polydactyly anomalies. Good motor function with acceptable aesthetic appearance was obtained.

Child↗

PubMed1995

A method of enhancing regeneration of conventionally repaired peripheral nerves.

The effect of axoplasmic fluid injection on regeneration of conventionally repaired nerve was studied. Twenty New Zealand rabbits were studied in two experimental groups: immediate nerve repair (Group 1A, no axoplasm; Group 1B, axoplasm injection) and delayed nerve repair (Group 2A, no axoplasm; Group 2B, axoplasm injection group). A total of 40 sciatic nerve repairs were performed. After epineurial nerve repair, axoplasmic fluid collected from the proximal and distal nerve stumps was injected under epineurium proximally and distally to the anastomotic site. In the two control groups (immediate nerve repair and delayed nerve repair, both without axoplasm), 0.9% saline was injected in a similar way. Nerve regeneration was assessed by measuring hair and nail growth, plantar and dorsal foot temperature, muscle atrophy, and the toe spread test. In the 3- and 6-month follow-up periods, nerve samples were taken for histological evaluation. Specimens were stained with toluidine blue, and 50% of the nerve cross-section area was counted from microphotographic reconstructions. After immediate repair in Group 1, axoplasmic fluid-treated animals showed a 27% increase in the number of myelinated axons at 3 months when compared with saline-treated controls (3,768 vs. 2,962 +/- 1,921 SD). After delayed repair in Group 2, a 32% increase in myelination axon counts was detected at 3 months in axoplasm-treated animals compared with saline-injected controls (1,040 +/- 684 SD vs. 786 +/- 389 SD). In addition, a positive toe spread test result was seen at 6 months in the axoplasmic fluid-treated animals.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗