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O M Folomeeva

Publications and source records attributed to O M Folomeeva.

At least 19 recordsLinked to original sources
PubMed2005

[The causes of death of patients with rheumatic diseases in Moscow].

The study was held in order to analyze the main causes of death in cases of rheumatic diseases (RD) in Moscow. The authors studied the pathology records of autopsies performed in 1999-2002 in two pathology departments of Moscow clinics. Cases with RD were selected. The study found 165 cases of RD, which constituted 2% of all autopsies performed in these departments. There were 99 cases (60%) of rheumatic heart disease (RHD), 4 cases (2.4%) of rheumatic fever (RF) relapse, 28 cases (17%) of rheumatoid arthritis (RA), 8 cases (4.8%) of systemic lupus erythematosus (SLE), 3 cases (1.8%) of scleroderma systematica (SS), 2 cases (1.2%) of ankylosing spondylitis (AS), 2 cases (1.2%) of systemic vasculitis (SPV), 11 cases (7.3%) of osteoarthrosis, 3 cases (1.8%) of gout, 1 case (0.6%) of polymyositis. The death of patients with RHD had been caused by hemodynamic decompensation (HD) in 54% of the cases, acute cardiovascular collapse (ACC) in 14% of the cases, 6% of the patients had died from thromboembolism (TE) and 26%--from other conditions (intoxication, uremia, brain and lung edema etc). The death of patients with RF was caused by TE in 2 cases, by HD in 1 case and by ACC in 1 case. Secondary amyloidosis resulting in chronic renal failure and uremia occurred in 5 out of 28 cases of RA, HD--in 3, ACC--in 7, TE--in 1, infectious complications--in 5, other complications--in 7 cases. Patients with SLE died from various conditions: uremia in 2 cases, acute adrenal failure in 1 case, infectious complications in 2, ACC--in 2, brain edema--in 1 case. The complications of SS were uremia and intoxication. ACC was the cause of death in cases of gout and SS. The majority of RD cases were patients with RHD. The main cause of death in RD was cardiovascular disorders.

Adult↗
PubMed2005

[Causes of death in patients with rheumatic diseases in Moscow].

AIM: To study causes of death of rheumatic patients in Moscow. MATERIAL AND METHODS: Autopsy protocols for 1999-2002 were analysed for two pathoanatomic departments of Moscow. RESULTS: Rheumatic diseases were detected in 165 cases (2.0% of overall number of autopsies in these departments). Rheumatic heart disease (RHD) was stated in 99 (60.0%) cases, rheumatic fever relapse (RFR) in 4 (2.4%), rheumatoid arthritis (RA) in 28 (17.0%), systemic lupus erythematosus (SLE) in 8 (4.8%), systemic sclerosis (SS) in 3 (1.8%), ankylosing spondilarthritis (AS) in 2 (1.2%), systemic vasculitis (SV) in 2 (1.2%), osteoarthrosis in 11 (7.3%), gout in 3 (1.8%), polymyositis in 1 (0.6%). RHD patients died of decompensated circulation (DC) (54%), acute heart failure (AHF) (14%), thromboembolism (TE) (6%), other causes (26%). RF patients died of TE (n = 2), DC (n = 1), AHF (n = 1). Out of 28 RA patients, 5 patients died of secondary amyloidosis, 3 of DC, 7 of AHF, 1 of TE, 5 of infectious complications, 7 of other causes. SLE patients died of uremia (n = 2), acute adrenal failure (n = 1), infectious complications (n = 2), AHF (n = 2), brain edema (n = 1). CONCLUSION: Among rheumatic diseases, rheumatic heart valve disease was most severe as it caused the highest mortality. Cardiovascular pathology caused death in most of the rheumatic patients.

Adult↗
PubMed2004

[Statistic-mapping modeling of rheumatic diseases prevalence among population of different regions of Russia].

AIM: To assess feasibility of the method of mapping modeling for spacial featuring of rheumatic diseases (RD) morbidity statistics for population of Russia. MATERIAL AND METHODS: Population morbidity statistics for 78 administrative units of the Russian Federation (1993-2000) were processed. Statistic-mapping modeling employed weighted mean interpolation i.e. mathematic prediction of the sign value depending on its magnitude in basic points. RESULTS: Mapped images of RD prevalence, prevalence/primary morbidity values and number of documented cases/number of rheumatologists demonstrate special distribution of the signs studied about the RF territory. The estimation of mean, minimal, maximal values and dispersion of each sign established dynamic trends in the markers for the period under study(increased area with RD prevalence above 95/1000 from 15.9 to 44.5%; increased mean ratio prevalence/morbidity from 2.8 to 3.2 and decreased ratio of patients/rheumatologists from 10882 to 9031). Regions with minimal and maximal values are shown. CONCLUSION: Statistic-mapping modeling demonstrates spacial distribution of the markers, reveals the relations between them.

Humans↗
PubMed2003

[Analysis of lethal outcomes of rheumatic diseases in Moscow].

AIM: To study the pattern of lethal outcomes due to rheumatic diseases (RD) in Moscow. MATERIAL AND METHODS: Annual reports of 38 pathological departments of Moscow have been analysed for 1999 and 2000. RESULTS: RD accounted for 1.8% diagnosis at autopsies (n = 784). RD as the main diagnosis was in 668 cases (1.53%). Diseases of the bone-muscle system caused death 3.5 times less often than rheumatism. As concommitent diseases RD were encountered in 118 cases (0.27%), diseases of the bone-muscle system were registered 2 times less frequently than rheumatism. Chronic rheumatic diseases of the heart were diagnosed in 590 cases (98.5%), rheumatic fever was detected in 9 (1.5%) patients. The main diagnosis of RA, seronegative arthritides, systemic vasculitides, SLE, osteoarthrosis was made in 49, 10 9.3, 12.7, 1.3%, respectively. Such nosological entities as osteoporosis, gout and other microcrystalline arthritides were referred to the group "other rheumatic diseases" and made up 12.7%. As concomitant pathology RA, OA, seronegative spondyloarthritides, SLE, other RD occurred in 54, 8.1, 27, 2.7, 2.7%, respectively. CONCLUSION: The share of RD in autopsy diagnosis accounts for 1.8% of the total number of necropsies. These figures seem to underestimate the real situation and may be explained by poor registration of RD at autopsy and a fall in the total number of autopsies for the last 10 years. For Moscow and Russia as a whole there is a prevalence of rheumatism mortality (76%), primarily deaths of chronic rheumatic cardiac diseases, over mortality due to diseases of the bone-muscular system (24%).

Autopsy↗
PubMed2003

[Russian society and patients with rheumatic diseases].

The morbidity, primary morbidity, temporary incapacity for work and disablement due to rheumatoid diseases registered among Russia's population in the recent 3 years are described on the basis of an analysis of Russian statistics. Issues related with mortality, caused by rheumatic diseases, the related expenses and influence on patients' life quality are under discussion. A conclusion is made on a high social-and-medical importance of the above category of diseases as viewed from the standpoint of society (state), patient and his or her family.

Adolescent↗
PubMed2002

[Incidence rate of rheumatic diseases in Russian population: 10-year analysis].

AIM: To analyze trends in rheumatic diseases (RD) incidence rate in population of Russia for a recent decade. MATERIAL AND METHODS: Medical RD statistics for all regions of Russia for 10 years (1990-1999) have been analysed. RESULTS: Annual number of primary patients with RD has increased for 1990-1999 from 9,147,000 to 12,378,000 (by 35.3%). The percentage of patients with acute rheumatic fever and chronic RD of the heart diminished from 6.5 to 2.9%. Most of the diseases constitute the diseases of osteomuscular system and connective tissue (DOMS). The number of new cases with rheumatic heart diseases (RHD) in adolescents and adults has risen by 50 and 40%, respectively. RHD are especially frequent in the Volga-Vyatka and North-Caucasian regions (2.5 and 2.3 per 1000 against mean Russian 1.7). A total DOMS morbidity has increased for the recent decade by 41%. It is higher in the Central and North regions, in the West Siberia and lower in the North Caucasus, Far East, East Siberia. For the 7 years the above morbidity among children rose 2-fold, among adolescents--2.4-fold. Incidence of rheumatoid arthritis and ankylosing spondylarthritis in adult population of Russia has changed insignificantly while osteoarthrosis total and primary occurrence for 6 years increased by 78 and 58%, respectively. CONCLUSION: RD become a real challenge for health service of Russia. Changes in RD structure require correction of the rheumatic service activities.

Adolescent↗
PubMed1996

[Rheumatism in the Russian Federation: statistic and reality].

According to the 1994 governmental statistics, 481353 patients with rheumatism (3.25 per 1,000 persons of all age groups) were notified in the Russian Federation. The prevalence of active rheumatism was 0.29%, that of chronic rheumatic heart disease was 2.96%. Among Russia's children, the spread of rheumatism was 0.8 per 1,000 children, the diagnosis of active rheumatism and chronic heart rheumatic diseases being made in 10,068 (31%) and 16,405 (0.5%) children. That of active rheumatism was first established in 12071 persons. Therefore, in 1994 primary incidence of acute rheumatic fever was 0.08 per 1,000 inhabitants of all ages and 0.18 per 1,000 children. The incidence rates of acute rheumatism among children and adolescents annually increased by 62%. This rise was solely due to the North-Caucasian region of the Russian Federation where the pediatric morbidity was 0.92%. The statistical findings are regarded as an alarming signal for the likelihood of acute rheumatic fever in the Russian Federation.

Humans↗
PubMed1991

[Acute transverse myelitis in patients with systemic lupus erythematosus].

The authors provide disease histories of 4 patients afflicted with genuine systemic lupus erythematosus (SLE). There were 2 men and 2 women who developed acute transverse myelitis (ATM) at an age of 24 to 31 years. Before ATM developed, SLE standing was from 3 to 10 years. Based on the authors' and reported data, the problems of the pathogenesis, clinical picture, diagnosis and prognosis in that grave complication of SLE are discussed. As for the mechanisms of ATM development, the role of antiphospholipid antibodies is reviewed. The data on familial aggravation of the patients are presented in terms of the development of the antiphospholipid syndrome in their relatives. Emphasis is laid on the necessity of early intensive care with glucocorticoid hormones and cyclophosphamide of patients with associated SLE and ATM in order to improve their prognosis.

Acute Disease↗
PubMed1990

[The use of a modified Health Assessment Questionnaire for evaluating the effectiveness of therapy at a hospital].

A study was made of a possibility of estimating the efficacy of hospital therapy of patients suffering from rheumatoid arthritis (RA) using the modified Stanford health assessment questionnaire. The general functional index (GFI) derived on the basis of the questionnaire was found to be in good agreement with a number of the commonly accepted indicators in rheumatology: Richi's articular index, the swelling index, the power of pain in accordance with the visual analog scale, hand force as well as with the psychological and social characteristics. The GFI was shown to decrease significantly after the treatment carried out under hospital conditions together with a decrease of pain and the articular index (p less than 0.001) both in grave RA patients with an unfavorable functional and work fitness prognosis and in patients with milder RA, having a favourable prognosis. It is recommended that the GFI may be used for estimating the efficacy of the treatment in addition to other indicators and measurements.

Arthritis, Rheumatoid↗