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Biomedical subjects

O Mickelsen

Publications and source records attributed to O Mickelsen.

At least 19 recordsLinked to original sources
PubMed1983

Bone mineral mass in adult lacto-ovo-vegetarian and omnivorous males.

Past studies indicate postmenopausal women who eat meat may experience greater bone mineral loss than lacto-ovo-vegetarian women. The present study extends those findings by comparing bone mineral in adult lacto-ovo-vegetarian and omnivorous males. Bone mineral mass was determined by direct photon absorptiometry in 320 lacto-ovo-vegetarian and 320 omnivorous males 20 to 79 yr old. Lacto-ovo-vegetarians were Seventh-day Adventists committed to their diet for at least 20 yr. Measurements were made at a cortical site along the radius. No statistical differences were identified between bone mineral mass in the lacto-ovo-vegetarian and omnivorous males in any decade examined. When contrasted against significant differences between bone mineral mass in postmenopausal omnivores and lacto-ovo-vegetarians, the data presented here may be interpreted as indicating that some factor associated with meat consumption is increasing bone mineral losses in postmenopausal females while having no observable effect in males.

Absorptiometry, Photon↗
PubMed1982

Dietary obesity in rats: influence on carbohydrate metabolism.

When male rats were fed a high diet from 3 to 20 weeks of age, they weighed 633 g which was 30% more than the animals fed a high glucose diet. Blood samples after a 16 to 18 hour fast, from the rats fed the high fat and high glucose diets contained, respectively: 130 +/- 11, 110 +/- 8 mg glucose/100 ml; 27 +/- 5, 24 +/- 3 microunits immunoreactive insulin (IRI)/ml; 791 +/- 58, 1104 +/- 179 meq nonesterified fatty acids (NEFA)/L. A tolerance test, by stomach tube, with 125 mg of glucose/100g body weight indicated that the rats fed the high fat diet had significantly higher mean plasma glucose concentrations, lower IRI responses and a lower leve of NEFA than rats fed a high glucose diet. Switching diets for 5 weeks resulted in body weights of about 600 g for both groups of rats. Those rats switched from the high fat to the high glucose diet did show an improved glucose tolerance, while the reverse was true of rats switched from the high carbohydrate to the high fat diet.

Animals↗
PubMed1977

Sodium and potassium intakes and excretions of normal men consuming sodium chloride or a 1:1 mixture of sodium and potassium chlorides.

Two groups of 10 healthy young men were matched on the basis of their free-choice consumptions of regular table salt. For 28 days they were then fed carefully controlled low-sodium foods. One group was permitted free-choice seasoning of these foods with regular table salt, the other with a 1:1 mixture of sodium and potassium chlorides. Intakes and urinary and fecal excretions of sodium and potassium were determined by analysis. The results were: 1) the subjects salted their food with essentially the same amounts of regular table salt as of the 1:1 mixture; 2) the sodium intake associated with seasoning at the table was reduced with the 1:1 mixture to 44 percent of the amount consumed with regular table salt; and 3) over a 28-day period there was no tendency for subjects to increase their use of a 1:1 mixture, when used in place of regular table salt, to compensate for their reduced sodium intakes. Under the conditions of this study, the use of the 1:1 mixture as a seasoning agent for foods that contained no added salt resulted in an average total intake of sodium (food plus seasoning) which was 55 percent that of the subjects using regular table salt.

Adult↗