Biomedical subjects
Publications and source records attributed to O Montgomery.
We report the first known case of chronic, massive fetomaternal hemorrhage managed by serial fetal intravascular transfusions. Timing of transfusions was guided by fetal heart rate patterns and fetal movement evaluation. Despite severe anemia and a sinusoidal heart rate pattern, the fetus demonstrated normal blood gases and no sign of hydrops.
The preventative effect of low-dose aspirin in the development of stress ulcer induced by cold restraint were examined in Sprague-Dawley rats. The bleeding and ulceration scores in the control group were 2.14 and 13.50, respectively. The bleeding score in the 1 mg/kg aspirin group was 1.32 and the ulceration score was 6.89. The scores in 50 mg/kg aspirin group were 2.86 and 38.74, respectively. A significant decrease of ulceration in low-dose aspirin and significant increase in high-dose aspirin were demonstrated. A significant decrease in gastric acid secretion in the low-dose aspirin group was recognized. However, the inhibition of platelet aggregation induced by low-dose aspirin was thought to play a major role in the prevention of stress ulcer.
The methods of daily routine analysis of urinary stones in one laboratory, employing a combination of microscopy, spectroscopy, chemistry, and X-ray diffractometry, are described. A methodologic study indicates that these methods are complementary and no one method is sufficient. Quantitative estimates are in general best obtained by X-ray diffraction, whereas qualitative identification of depositional sequence and the quantitative determination of minor constituents must depend on microscopic and chemical methods. Components at a concentration of 1 per cent may be identified whereas those in excess of 5 per cent are rarely overlooked. Concentrations are correct within +/- 10 per cent of stone mass.