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Biomedical subjects

O Muren

Publications and source records attributed to O Muren.

11 recordsLinked to original sources
PubMed2001

No bone ingrowth into the tibia tunnel in anterior cruciate ligament-reconstructed patients: a 1-year prospective quantified CT study of 10 patients reconstructed with an autologous bone-patellar tendon-bone graft.

10 patients with major instability symptoms due to an acute anterior cruciate ligament injury were operated on with a bone-patellar tendon-bone reconstruction. Tibial condyle bone mineral density (BMD), bone ingrowth and changes in diameter in the tibia bone tunnel were studied with quantified computed tomography (QCT) postoperatively and after 1, 3, 6 and 12 months. We found no sign of bone ingrowth in the form of increased bone mineral density (BMD) in the bone tunnels in any of the patients. The tunnel diameter increased in all patients during the first postoperative months. After 1 year, 5 patients had a smaller diameter than at the first postoperative examination, 2 had the same diameter as immediately after surgery and 2 patients had a larger diameter. A sclerotic zone developed in all patients along the perimeter of the tunnel during the 3-6 months of follow-up. The BMD in the tibial condyle decreased at 3 months; it then increased, but between 6 and 12 months, it levelled out and was slightly lower than postoperatively. In conclusion, we found no growth of bone into the tunnel and tendinous part of the graft during the first postoperative year.

Adult↗
PubMed1995

Reconstruction of old anterior cruciate ligament injuries. No difference between the Kennedy LAD-method and traditional patellar tendon graft in a prospective randomized study of 40 patients with 4-year follow-up.

In a prospective randomized study we investigated 40 patients with functional instability due to old anterior cruciate ligament tears by using two different techniques for reconstruction of the ligament. 20 patients were randomized to reconstruction with use of a traditional medial bone-patellar tendon graft and 20 patients to a half-thickness patellar tendon graft augmented with the Kennedy Ligament Augmentation Device (LAD). At follow-up after 4 years, both groups were still improved concerning function scores and arthrometry. The use of the Kennedy LAD method, however, gave no more subjective or objective benefits than did the traditional method.

Adolescent↗
PubMed1986

Prolonged isoflurane anesthesia in status asthmaticus.

We report a case of status asthmaticus that was unresponsive to the usual agents. The use of an inhalational anesthetic agent allowed us to ventilate the patient with lower inspiratory pressures; however, lasting improvement did not occur until she mobilized large quantities of secretions. To our knowledge, this is the first clinical report on the use of isoflurane anesthesia to treat severe asthma. Despite prolonged administration, there were no significant side-effects. This case demonstrates both the benefits and limitations of such therapy.

Adult↗
PubMed1979

Sarcoidosis presenting as a unilateral hilar mass.

Sarcoidosis has been characterized by a variety of clinical presentations ranging from complete lack of symptoms to incapacitating multisystem disease. Bilateral thoracic lymph node enlargement with or without pulmonary disease is the most common presentation. An elderly woman with eye pain, visual disturbance, nonproductive cough, and weight loss was found to have unilateral hilar enlargement on roentgenographic examination of the chest. An aggressive search for a neoplastic process disclosed only noncaseating granulomas consistent with sarcoidosis. The patient completely recovered on corticosteroid therapy alone.

Adrenal Cortex Hormones↗