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Biomedical subjects

O Myking

Publications and source records attributed to O Myking.

29 records · Page 2Linked to original sources
PubMed1980

The effect of serum from obese and normal weight men on glucose metabolism in leucocytes.

The influence of pooled serum from either obese or normal weight males on glucose metabolism in human leucocytes has been studied. Leucocytes from normal weight males were incubated with 10-90% pooled serum and either [U-14C], or [1-14C]glucose. Compared to serum from the normal weight males, serum from the obese group had a more stimulating effect on the 14CO2 and [14C]lactate production from [U-14C]glucose and on the 14CO2 production from [1-14C]glucose. The two serum pools had the same stimulating effect on the Embden-Meyerhof pathway as indicated by the formation of [14C]lactate from [1-14C]glucose. Calculations revealed that the activity in the pentose phosphate pathway was stimulated more by serum from obese, than from normal weight males. It is a possibility that increased stimulation of the pentose phosphate pathway may contribute to the development of overweight.

Adolescent↗
PubMed1975

The glucose oxidation in isolated leukocytes from female patients suffering from overweight or anorexia nervosa.

Leukocytes from controls and patients with either overweight or anorexia nervosa were incubated with [U-14C]glucose in buffer with or without 50 percent serum. The production of [14C]O2 was measured both under phagocytosing and nonphagocytosing conditions. On the average leukocytes from the two groups of patients produced less [14C]O2 than leukocytes from the controls. Sera from controls stimulated the glucose oxidation in control leukocytes more than sera from patients with anorexia nervosa and less than sera from overweight patients. Neither the insulin nor the glucose content of the sera was of importance for the results. We assume that other serum factors may contribute to the reduced glucose oxidation in leukocytes from patients with anorexia nervosa, whereas this is not the case for patients with overweight.

Adolescent↗
PubMedDate not supplied

Brief uncontrollable stress and psychological parameters influence human plasma concentrations of IgM and complement component C3.

Thirty-eight men participated in a study of immunological, hormonal, and psychological parameters before and after acute stress situations. A brief but acute stress was repeated daily for 4 days. This exposure caused the plasma levels of IgM and C3 to increase from Basal Day to Experimental Day 4. Significant correlations between endocrine and immunological parameters, and also between psychological measures and immunological parameters, were found. Use of psychological defense was related both to endocrine and immunological changes. The authors concluded that psychological stress may influence immunological functions both indirectly, by hormonal changes, and directly, by nervous regulation during brief but acute stress periods.

Adult↗