Biomedical subjects

O N Kriukovskikh

Publications and source records attributed to O N Kriukovskikh.

8 recordsLinked to original sources

PubMed1993

[Electrophysiological methods in assessing the risk for the development of multiple sclerosis in adolescents with monosymptomatic optic neuritis].

Pattern electroretinograms and visual evoked potentials (VEP) were investigated in response to reversal checker-board patterns with different sizes of checks in 13 adolescents with monosymptomatic optic neuritis in acute period and in the course of convalescence 1-2 and 12-36 months after the disease onset. All the children underwent computer tomography of the orbit and brain. The results allowed identification of high and low multiple sclerosis risk groups. The high risk can be proved by a progressive increase of VEP latency 1-2 months after the disease onset and its significant advance in later period of optic neuritis. Normal VEP latency in late optic neuritis shows a low degree of its development.

Acute Disease↗

PubMed1984

[Responses and organization of the receptive fields of neurons of the basal optic nucleus of the frog tegmentum during visual stimulation].

Stationary visual stimuli and diffuse light induced mainly excitatory responses of the neurons. Among the neurons responding to visual stimulations many units were the polysensory cells responding also to tactile and sound stimuli. The questions of organization of the tegmental neurons' visual receptive fields, are discussed. Prevalence of large receptive fields has been noted, mainly excitatory those or having an excitatory center and inhibitory periphery.

Animals↗

PubMedDate not supplied

[Visual evoked potentials in children with congenital glaucoma].

Phasic and established visual evoked potentials (VEP) to homogeneous light field and chess patterns were studied in 25 patients (48 eyes) aged 1.5 months to 9 years with different stages of congenital glaucoma and in 114 age-matched healthy children. Patients with almost absolute and far progressed stages of the disease presented with gross changes of VEP to both large- and small-cell chess patterns. In patients with the initial stages of decompensated congenital glaucoma VEP to mostly large-cell chess patterns were altered. These data evidence the usefulness of examining the VEP to stimuli with low spatial frequency for the early detection of congenital glaucoma.

Age Factors↗

PubMedDate not supplied

[Visual evoked potentials in chessboard pattern reversion in children with optic neuritis].

Visual evoked potentials (VEP) to chess pattern reversion were studied in 17 children with optic neurites during the acute stage and in the course of convalescence 1-2 months and 1-3 years after the disease onset. Coarse VEP changes were detected in the patients during the acute stage of optic neuritis. A positive time course of VEP was followed up in late periods after the acute attack of the disease. Despite normalization of vision acuity, no complete restoration of VEP to small-cell chess patterns was seen. The findings evidence that studies of VEP to chess pattern reversion should be carried out to detect subclinical involvement of the optic nerve and to timely diagnose optic neuritis in children.

Acute Disease↗

PubMedDate not supplied

[Visual evoked potentials in the evaluation of visual acuity in infants].

Vision acuity was assessed by visual evoked potentials (VEP) in response to low-frequency chess pattern reversion in 31 full-term healthy babies aged 6 to 28 weeks. The mean vision acuity of babies aged 6 to 9 weeks was 0.5 +/- 0.01, of those aged 16 to 18 weeks 0.1 +/- 0.01; in babies aged 24 to 26 weeks vision acuity was at least 0.14, but still lower than in normal-sighted adults. The authors emphasize the advantages of low-frequency chess pattern reversion in assessment of vision acuity from VEP in babies.

Adult↗

PubMedDate not supplied

[Electrophysiological and neuroradiological methods in the diagnosis and prognostication of functional outcome in young children with lesions of the visual tract].

The authors analyze the data of computer-aided tomography, neurosonography, and visual evoked potentials to chess pattern reversal in 14 infants aged 6 to 11 months with partial atrophy of the optic nerve and/or visual cortex involvement before and in various periods after transcutaneous electric stimulation combined with neurotrophic drug therapy. The advantages of comprehensive examinations in neuroophthalmological diagnosis in infants are shown, as is the possibility of using electrophysiological and neuroradiological methods for prediction of functional outcomes in the said patient population.

Age Factors↗

PubMedDate not supplied

[The effect of occlusion of the better seeing eye on the function of the visual system in children with unilateral amblyopia].

Vision acuity and visual evoked potentials (VEP) to a homogeneous light field and chess field reversion were studied in children aged 5-6 years with unilateral amblyopia before and after 3-month direct total occlusion of the intact eye. Occlusion of the intact eye resulted in improvement of the vision acuity and VEP of the amblyopic eye, that correlated with the degree of amblyopia. At the same time examinations of the intact eyes revealed reduced amplitude of VEP to large and increased latency to small chess pattern cells but no changes of the vision acuity. The results evidence the necessity of monitoring the occlusion by VEP recording to prevent the detrimental effects of visual deprivation on the development of the system of vision in a child.

Amblyopia↗

PubMedDate not supplied

[Changes in contrast sensitivity in children with optic neuritis].

Changes of spatial contrast sensitivity (SCS) were studied in children with optic neuritis in the acute, convalescent, and remote periods of disease. A selective reduction of SCS of involved and intact eyes in the high frequency band was revealed, indicating the predominant involvement of the parvocellular subsystem of vision in optic neuritis. A correlation of SCS disorders with abnormalities of visual evoked potentials was revealed. The detected regularities indicate shifts on the part of the retrochiasmal structures in patients with optic neuritis, this being confirmed by studies making use of computer-aided tomography and magnetic imaging.

Adolescent↗