Biomedical subjects
Publications and source records attributed to O N Kurennaya.
We propose a method for standardization of complex adaptogen-containing preparations. The method is based on acceleration of baking yeast strain growth on energy-depleted medium in the presence of the test agent. This method allows simple quantitative biological control of phytoadaptogens and comparison of adaptogenic activity of mono- and complex preparations.
A strain of fission yeast carrying replicating instability (RI) will segregate mitotically three types of cells: unstable (still RI-carrying) cells, stable identical mutants and stable non-mutants. RI in fission yeast has previously been considered as a specific type of premutational lesion capable of (1) being replicated as such and (2) reverting at an appreciable rate to the normal state as well as changing into a stable mutation. In the present work genetic analysis of a previously studied RI-carrying strain showed this strain to be a diploid, most probably heterozygous for a recessive mutation. It was possible to construct other unstable heterozygous strains segregating predetermined mutants but not to induce RI by UV-irradiation of haploid cells. Thus evidence is presented against the premutational nature of RI in fission yeast.
Explore the source record for details and available documents.
Explore the source record for details and available documents.