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Biomedical subjects

O N Smirnova

Publications and source records attributed to O N Smirnova.

8 recordsLinked to original sources

[A trial to decrease hepatitis A morbidity in Dzerzhinsk, Gorki Province].

The results of experience in the comparative evaluation of the preseasonal immunoglobulin prophylaxis in two towns of the Gorki Province are presented. The work substantiates the economic and epidemiological effectiveness of immunoglobulin prophylaxis at the territory, relatively safe with respect to hepatitis A, under the conditions of its realization in the year of the predicted rise of morbidity, the timely organization of immunoglobulin prophylaxis (from July to the first half of October) and the coverage of "organized" children, exceeding 90%.

Child

[Brief review of documents with data on the toxicity and hazards of chemical substances developed in various countries].

Nowadays various information documents on toxicity and danger of chemical substances exist, i. e., toxicologic certificates, data profiles, trade certificates, etc. An attempt has been made to analyze 15 available data lists used in various countries for the description of noxious and hazardous characteristics of chemicals. The indices on toxicity and danger of chemicals enumerated in the lists are grouped by 9 main categories. The degree of detailed description of the data presented is determined by the aim of the document. The results thus obtained can be used in the further work aimed at the improvement and unification of the forms providing the data on toxicity and danger of the chemicals.

Canada

[Comparative clinico-morphological characteristics of the variants of adeno-squamous carcinoma and adenocarcinoma of the endometrium].

A clinico-morphological analysis of the data available on cases of adeno-squamous carcinoma (72) and endometrial adenocarcinoma (102) pointed to a correlation between the decrease in the degree of cell differentiation in said neoplasms and the decline in the frequency of hyperestrimism and metabolic-endocrine disorders. As a result over 70% of well-differentiated cell tumors were referred to one pathogenetic pattern of endometrial carcinoma (after Bokhman) and more than 50% of poorly-differentiated cell tumors--to another one. These findings further support the rationale for distinguishing the well- and poorly-differentiated cell patterns of adeno-squamous carcinoma. They may be used in establishing individual prognosis as well as choosing optimal scheme of treatment.

Adenocarcinoma