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Biomedical subjects

O N Voskresenskiĭ

Publications and source records attributed to O N Voskresenskiĭ.

At least 19 recordsLinked to original sources

[Effect of antioxidants on the indices of free-radical lipid oxidation in the testes of rats of different ages and on the reproductive capacity in chronic multiple antioxidant deficiency].

The free-radical oxidation level of lipids in the rat's testicles of different age under the conditions of chronic and multiple antioxidant insufficiency has been studied, as well as the reproductive ability of male rats, kept at the nonantioxidant ration. The increase of free radical oxidation lipids in the testicles of animals with chronic multiple antioxidant insufficiency and the decrease of their reproductive ability has been observed. The antioxidant complex in such conditions had a defensive effect. The obtained results serve as the basis of the antioxidant use as the means of normalising the reproductive functions in males during period of low receipt and high expense of alimentary oxidants.

Aging↗

[Ultrastructure of the inner surface of the aorta of mature and old animals].

In the experiments, performed on 12 white rats and 8 rabbits, by means of scanning electron microscopy of the native preparations and in a number of cases with use of silver nitrate impregnation, the internal surface structure has been studied in the aortal membrane of mature and old animals. At ageing the integrity and continuity of the endothelial monolayer is preserved, on the surface local intimal pits, craters and microdefects appear, adhesiveness of endothelium to leucocytes increases. Orientation of the intimal folds is disturbed. The type of the senescent remodeling in the endothelial layer revealed predisposes to development of atherosclerosis.

Aging↗

[Lipid free-radical oxidation in cerebral arteriosclerosis patients in relation to the stage of the disease].

Patients with cerebral atherosclerosis were examined for the parameters of lipid and peroxidation metabolism and their correlation with the gravity of the disease. The findings obtained included the development of moderate hyperlipidemia and intensification of lipid free radical oxidation. The levels of hyperlipidemia showed no significant variations in patients with cerebral atherosclerosis of varying severity whereas the levels of free radical oxidation of lipids directly correlated with the severity of the disease. The processes of free radical oxidation play a significant role in the pathogenesis of cerebral atherosclerosis.

Adult↗

[Effect of chronic emotional stress on lipid peroxidation in the tissues and blood of emotional and nonemotional rats].

The effect of chronic emotional stress on lipid peroxidation (LP) in tissues and blood was studied in "emotional" and "nonemotional" rats. In was established that the content of LP products in the brain, liver and myocardium, the blood content of beta- and pre-beta-lipoprotein hydroperoxides, and peroxide resistance of red blood cells were higher in "emotional" than in "nonemotional" animals. The stress-induced increase in the individual differences as regards LP correlates with the intensity of the pathological somatic manifestations.

Animals↗