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Biomedical subjects

O Nahlieli

Publications and source records attributed to O Nahlieli.

At least 19 recordsLinked to original sources
PubMed2006

Sialadenitis following radioiodine therapy - a new diagnostic and treatment modality.

OBJECTIVES: To explore the usage of salivary gland endoscope technique as a diagnostic tool as well as a novel treatment modality for sialadenitis following radioiodine therapy. SUBJECTS AND METHODS: Fifteen patients suffering from sialadenitis of the major salivary glands after I131 therapy for thyroid carcinoma underwent a single procedure of sialoendoscopy under local anesthesia. RESULTS: All the patients were free of sialadenitis after one sialoendoscopy procedure with no complications accompanied. CONCLUSIONS: Sialoendoscopy is an efficient technique with low morbidity as well as a relatively simple surgical method for diagnosing and treating sialadenitis induced by radioiodine therapy for thyroid cancer patients.

Endoscopy↗
PubMed2004

[Future therapy strategies for salivary gland impairment].

Saliva offers many modalities, mainly protecting the oral tissues by maintaining a local healthy environment. Several conditions cause salivary gland secretion impairment, in which irradiation therapy to the head and neck cancer patients is one of the most rigorous, leading to major decline in quality of life. At present, conventional therapy provides a limited answer for this situation. In the last two decades, several strategies had been proposed to overcome this problem. These approaches can be divided into three branches: 1. Preventing salivary gland damage before irradiation therapy. 2. Protecting the secretory parenchymal tissue during the course of irradiation and, 3. Trying to regenerate salivary gland function after irradiation damage has already occurred. These attitudes may provide future beneficial modalities to salivary gland dysfunction especially in patients were salivary gland function is diminished.

Amifostine↗
PubMed2003

[Nerve injury following implant placement: prevention, diagnosis and treatment modalities].

Nerve injury is a well-known complication following oral and maxillofacial surgery. Direct trauma, inflammation and infection are postoperative neural disturbances main causes. The most inflicted nerves associated with endosseous implant placement are those innervating the mandible: the inferior alveolar nerve, the mental nerve and the lingual nerve. Evaluation of the nerve injury characteristics and severity as early as possible has always imposed a great challenge for clinicians. We demonstrate a reliable yet simple way of dealing with this kind of problem in conjunction with comparing preoperative and postoperative sensation of the chin, the tongue and the lower lip. On the other hand, it is considerably important to take preventive measures for such injuries by using appropriate radiographic images. If a nerve damage has occurred, best prognosis is to be expected by early and appropriate treatment. It is imperative to treat such injuries in four months following the injury, otherwise a permanent nerve damage may occur. Further investigation of nerve damage risks following implant placement should be performed in order to enable patient to decide whether having implants dependent rehabilitation or choosing an alternative.

Cranial Nerve Injuries↗
PubMed2002

Harnessing the osseointegration principle for anchorage of fingernail prostheses.

On the basis of this preliminary report series of patients, it seems that the achievement of fixed anchorage for nail prostheses is feasible using the process of osseointegration, the use of standard dental implants, and abutment and maxillofacial rehabilitation laboratory to build the superstructure system. The osseointegrated procedure is relatively simple, cost-effective, and less time-consuming compared with other reconstruction techniques. Using local anesthesia and day-care facilities the operative time was only 35 minutes for the first stage and 15 minutes for the second stage. The attachment should be lifelong, as in the face. Loosening and infection are infrequent.

Adolescent↗
PubMed2001

Povidone-iodine related burns.

Skin preparation burns associated with chemical agents are uncommon. They occur most frequently in patients placed in the lithotomic position undergoing gynaecologic or urologic operations, the burn being on the buttocks, and in those undergoing orthopaedic operations, the burn being on the extremities and under a tourniquet. The basic mechanism involves irritation coupled with maceration and pressure. If the betadine solution has not been allowed to dry and has been trapped under the body of the patient in a pooled dependent position, such as the buttocks or under a tourniquet, the solution may irritate the skin and result in a skin burn. The irritation coupled with pressure leads to a situation analogous to that seen in the development of an acute accelerated decubitus ulcer; irritation, maceration, friction and pressure compounding each other to result in a skin burn or superficial ulcer in the skin. Our experience with three illustrative patients who presented with various burns following exposure to povidone-iodine (betadine) is described below.

Administration, Topical↗
PubMed2001

Diagnosis and treatment of strictures and kinks in salivary gland ducts.

PURPOSE: This article describes the use of sialoendoscopy for diagnosis and treatment of strictures and kinks in the major salivary glands ducts. PATIENTS AND METHODS: Thirty-four salivary glands with obstruction were diagnosed as having ductal kinks or strictures. Strictures were diagnosed by sialography and sialoendoscopy, kinks were diagnosed mainly by sialography, whereas endoscopy was used to rule out other pathology and to locate the kink. There were strictures in 25 salivary glands (14 male and 11 females; aged 25 to 60 years), 14 in the parotid and 11 in the submandibular gland, and kinks in 9 salivary glands (5 males 4 females; aged 40 to 55 years). Seven kinks were found in the submandibular gland and 2 in the parotid. Treatment of strictures was performed by dilatation procedures with saline under pressure, balloon techniques, and forced manipulation. After these procedures, a polyethylene stent was inserted for 2 weeks. Kinks were treated by advancement ductoplasty and balloon contouring to overcome the acute angle. RESULTS: Twenty of 25 cases of stricture became completely asymptomatic in a follow-up of 8 to 36 months after treatment. In 4 cases, further revisional dilatation was needed, and in 1 case treatment failed and the gland had to be removed. All 9 cases of kinks became completely asymptomatic in a follow-up of 6 to 24 months after treatment. CONCLUSION: Strictures and kinks should be considered when salivary gland obstruction is present without sialolithiasis.

Adult↗
PubMed2001

Autologous blood injection for treatment of recurrent temporomandibular joint dislocation.

OBJECTIVE: The purpose of this study was to reintroduce a rather simple, safe, minimally invasive, and rapid alternative procedure for the treatment of recurrent dislocation of the condyles. STUDY DESIGN: Subjects were 3 patients (5 joints) who suffered from recurrent condyle dislocation. The technique consisted of visually identifying a line from tragus to the eye angle. Then the articular fossa point was identified in this line, 10 mm anteriorly to tragus and 2 mm below the line. A 19-gauge needle was inserted at the articular fossa point. After injection of saline in the superior compartment, 5 cc of autologous blood drawn from the cubital fossa was injected (4 cc in the superior compartment and 1 cc in the pericapsular tissue). After this an elastic bandage was applied and left for the first 24 hours. Patients were advised to constrain their mandibular motion and to eat only soft foods for a week. They received cephalosporin antibiotics and nonsteroidal anti-inflammatory drugs for 7 days. A week after the procedure, supervised physiotherapy was started and the patients were encouraged to increase their mandibular opening to 40 mm. RESULTS: Postoperative recoveries were uneventful. Dislocation of condyles did not reoccur; however, patient no. 3 experienced an episode of unilateral subluxation. At follow-up all patients presented with normal mouth opening. CONCLUSION: Bleeding resulted from the introduction of a needle for injection in the pericapsular tissue. Blood coming from this wound, associated with autologous blood injected in the superior compartment, generates a bed for fibrous tissue formation in the region, creating a limitation of mandibular movement, thus ceasing dislocation of the condyles. Temporomandibular joint autologous blood injection is a simple procedure performed on an outpatient basis that we advise as an alternative treatment for patients with recurrent dislocation of the condyles.

Adult↗
PubMed2000

Accessory parotid gland masses.

Three cases of accessory parotid gland lesions are reported. The literature concerning accessory gland disease and its diagnosis and treatment is reviewed.

Adenoma, Pleomorphic↗
PubMed2000

Pediatric sialolithiasis.

Pediatric sialolithiasis is a rare condition. This article characterizes 15 cases in children between 5 and 14 years of age. The diagnoses of this condition were made with routine radiograph and ultrasound, as well as with sialography whenever possible. Sialoendoscopy was performed as a diagnostic and treatment modality. Thirteen of the 15 affected children were boys, and 12 of 15 cases occurred in the submandibular gland. We were able to diagnose 67% by our imaging methods; the remainder were diagnosed by clinical examination.

Adolescent↗
PubMed2000

Long-term experience with endoscopic diagnosis and treatment of salivary gland inflammatory diseases.

OBJECTIVES: To assess the efficacy of the sialoendoscopic technique for treatment of inflammatory salivary gland diseases. This report documents the authors' long-term experience with sialoendoscopy and discusses the long-term results of the procedure, technical issues, and varieties that they have utilized, as well as the advantages and limitations of this modality. STUDY DESIGN: Retrospective clinicopathologic study of 236 patients who were endoscopically treated from 1994 to 1999 for suspected salivary gland obstructive disease. METHODS: Endoscope employed was the third generation sialoendoscope (Nahlieli Sialoendoscope, Karl Storz, Tuttlingen, Germany). RESULTS: Ten sialoendoscopies were immediate failures as a result of technical problems. In the remaining 226 glands, 170 had obstructions and 56 had sialadenitis without evidence of obstructions. The success rate was 83%. Multiple endoscopic findings were encountered. No severe complications were noted. CONCLUSION: This report demonstrates the efficacy and safety of sialoendoscopy as a promising new method for use in the diagnosis, removal, and postoperative management of sialolithiasis, sialadenitis, and other obstructive salivary gland diseases.

Adolescent↗