PubMed Health⌕ Search

Biomedical subjects

O O Akute

Publications and source records attributed to O O Akute.

9 recordsLinked to original sources
PubMed2005

Bile duct stricture -- a sign of things to come?

OBJECTIVE: The aim of the report is to highlight this difficult to-treat condition hitherto uncommon in our environment and warn of the likelihood of more to come with the rising incidence of gallstone in our sub region. PATIENT AND METHOD: A case report of an 18-year-old male undergraduate patient. RESULT: A successful management with clinical, biochemical and radiological evidence (OTC and tubograms) despite inadequate investigative tool. PRINCIPAL CONCLUSION: With the rising incidence of gall stones in our environment, it is imperative that the Trainee Surgeon must be schooled in common biliary surgery and help prevent this dreaded complication (bile duct stricture) and other sequelae of gall bladder surgery. A plea is also made for the provision of essential investigative tool to facilitate management of such cases in recognised centers.

Adolescent↗
PubMed2005

Familial thyrotoxicocis in five Nigerians.

We describe the occurrence of thyrotoxicosis in four Nigerian families. Hitherto. the descriptions of familial thyrotoxicosis have been confined to the Caucasian population and only recently in a Chinese family. This is the first description of familial thyrotoxicosis in the Nigerian population. The mutation analysis of the genomic DNA of the TSH receptor of these patients is required to define the genetic mutations that caused the disease. We recommend that a high index of suspicion for familial thyrotoxicosis should be exercised in the clinical evaluation of patients who present with hyperthyroidism.

Adult↗
PubMed2004

Necrotizing fasciitis.

Necrotizing fasciitis (NF) is a rare but rapidly progressive and potentially fatal disease condition. It is characterized by progressive inflammation and extensive necrosis of the subcutaneous tissue and fascia, sparing the underlying tissue. It is a poly-bacterial infection and is associated with profound systemic toxicity, considerable morbidity and a high mortality rate. The outcome is influenced by early recognition and radical surgical debridement. We present a report of six cases of NF who presented to our surgical service within the past 5 years.

Adolescent↗
PubMed2003

A review of gall bladder carcinoma in Ibadan.

Twenty cases of histologically proven carcinoma of the gall bladder (GB) seen in the University College Hospital, Ibadan, Nigeria between 1983 and 1997 were reviewed. There were seven males and thirteen females, thus giving a sex ratio of 1:2. The majority of the cancers occurred between the fourth and seventh decade of life. The pre-operative diagnosis has improved and about 70% of the ten patients with adequate clinical information had definitive surgical treatment. The advent of new imaging techniques at this hospital, consisting of ultasound (US) and computerized axial tomography(CT) has made pre-operative diagnosis possible. This is in contrast to the situation noted twenty years earlier in a similar study. Surgical intervention can now be timed and planned appropriately in the majority of cases although late presentation is still a problem. With earlier presentation, prompt diagnosis and appropriately planned surgery, a better survival figure is anticipated at this institution.

Adult↗
PubMedDate not supplied

Colorectal carcinoma in Ibadan, Nigeria: a 20-year survey--1971 to 1990.

BACKGROUND/AIMS: Five hundred and four (504) cases of histologically proven adenocarcinoma of the large bowel were seen in the University College Hospital, Ibadan, between 1971 and 1990. The rise in incidence predicted by the writers in the seventies is confirmed but it is feared that the economic depression may make alternative medicine attractive and turn patients away from the hospitals. The sex ratio has approached that seen in the West but the average age incidence has not changed. METHODOLOGY: One hundred and forty-one (141) case notes were available for critical evaluation. RESULTS: These case notes show that patients still present rather late and some still find the idea of terminal colostomy sufficiently repugnant to refuse surgery. This disease is no respecter of persons and the clinical features are in no way different from those already recorded. Most of the colonic tumors are located on the right side of the colon. This has been the pattern in the African population--a phenomenon now reported frequently in the West. CONCLUSIONS: The colon/rectum ratio has been reversed in favor of the rectum but unfortunately, this has not had a positive influence in early presentation and diagnosis. The "silent majority" on the right side of the colon can only add to the problem of late presentation. A plea is, therefore, made for adeq-uate investigations of 40 years old and above presenting with vague pain in the right iliac fossa and/or features of hemorrhoids which may herald carcinoma on the right and left, respectively.

Adenocarcinoma↗
PubMedDate not supplied

Prevalence of gall stones in a group of antenatal women in Ibadan, Nigeria.

The prevalence of gall stones in Africa is low even though this varies from one part of the continent to another. The few studies were hospital based and excluded majority of silent stones. Abdominal ultrasounds were carried out prospectively on 4,214 consecutive patients referred to an ultrasound centre which cares primarily for pregnant women--a well known vulnerable group for gall stones. An overall prevalence rate of 2.1% was found. This represents a 300-fold increase over previous figures in Ibadan albeit from a different study group. A further study of the disease in the general population is necessary, though it is suggested that the figure in the general population may be less. When this figure is compared with the 10 to 20% in Europe and North America, it confirms the low incidence of the disease in our environment. Majority of the stones were asymptomatic (95%). This needs to be confirmed in the general population. The average stone former in our environment as in previous study does not conform to the classical caucassian description.

Adolescent↗
PubMedDate not supplied

Cholelithiasis in Ibadan: an update.

This study is to ascertain the present status of cholelithiasis in our environment. Six hundred and seventy (670) consecutive abdominal, ultrasounds done for various abdominal complaints at the University College HospitaL Ibadan from January 1977 to December 1998 were studied for gall stones in addition to other studies of the abdomen. Only twelve (12) gallstones were found, giving a prevalence of 1.79%. Only 25% were silent stones. The male:female ratio was 1:3. The mean age was 30 years (S.D = 2.8) and peak age was between 30 and 40 years. The average body mass index (B.M.I) was 23.49 kg/m2 (S.D = 3.9). The average parity among the women was four (4). Only one ultrasound was false (false negative). This study shows an increase. In prevalence over previous figures (1.79%) as against 0.007% in the sixties). The peak age is a decade lower and the anthropometric measurements in our patients do not support the typical caucassian model.

Adult↗