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Biomedical subjects

O O Makinde

Publications and source records attributed to O O Makinde.

18 recordsLinked to original sources

Trends in utilization of obstetric care at Wesley Guild Hospital, Ilesa, Nigeria. Effects of a depressed economy.

Perinatal mortality rate (PNMR) at Wesley Guild Hospital (WGH), Ilesa, Nigeria, over a ten-year period was retrospectively analysed. The main objective was to determine the trends in the utilization of obstetric care and PNMR in the face of current economic difficulties in Nigeria and to make suggestions for improvement. The average PNMR over the period was 57.8/1000 births. There was a sharp rise in PNMR in 1985 to a peak of 110/1000 in 1987 (p < 0.0001). This was associated with a decline in utilization of maternity services, probably as a result of the introduction of fees for maternity services late in 1984 and increase in economic hardship in Nigeria. Actions are needed to improve enhanced access to obstetric care for the poor. These actions include: improvement in the economic conditions of the people, emphasis on primary health care (PHC) and early referral of high-risk pregnant women to tertiary units.

Developing Countries↗

Maternal tetanus toxoid coverage during pregnancy in Ile-Ife, Nigeria.

A cluster survey on maternal tetanus toxoid (TT) coverage was carried out in the Ile-Ife Central Local Government Area. Out of the 896 mothers of babies 0-12 months old who were interviewed, 668 (74.6%) claimed they received TT during pregnancy, this was confirmed in 37 (4.1%) and in only 25 (2.8%) of these cases could the babies be said to have been protected from neonatal tetanus (NNT) at birth. About 35% of the babies were delivered at home/churches where most babies with NNT are usually born.

Adult↗

Biosocial factors affecting menarche in a mixed Nigerian population.

A prospective study of school girls in a mixed Nigerian population revealed that the mean menarcheal age was 13.98 +/- 1.30 years. The mean menarcheal age was influenced by the social class of the parents, being higher in the lower social class, there were considerable variations in the biologic measurements (height, weight and body mass index) among girls who attained menarche.

Adolescent↗

Ureteric injuries associated with gynecologic surgery.

We conducted a review of eight ureteric injuries associated with major gynecologic surgery in seven patients over an 11-year period. Our low incidence of 0.36% is comparable with other reports. Diagnosis was made either intra-operatively or postoperatively. Immediate ureteric repair is advocated for all injuries discovered intra-operatively. Attention to preventive measures both before and during gynecological operations will reduce the incidence of ureteric injuries.

Adult↗

Ectopic pregnancy in a defined Nigerian population.

All cases of ectopic pregnancy in the Ile-Ife teaching hospital between 1977 and 1987 were reviewed. The incidence per 1000 births was 4.76, and this condition accounted for 2.75% of all gynecological admissions. The associated mortality was low (0.5%). An increasing incidence was observed during the study period, as was an increasing proportion of nulliparous patients. Tubal damage from pelvic infections might account for the trends.

Female↗

Gravid uterus in an anterior abdominal wall hernia of a Nigerian woman.

A case of a gravid uterus in an incisional hernia in the anterior abdominal wall of a 27-year-old Nigerian woman is presented. The patient developed an ulceration of the anterior abdominal wall necessitating prolonged hospitalization. She was delivered by emergency lower segment cesarean section at 35 weeks gestational age because of premature labor. The patient unfortunately died from primary postpartum hemorrhage.

Adult↗

Bilateral tubal and twin pregnancies in Ile-Ife, Nigeria.

Three cases of unilateral tubal twin pregnancies and four cases of simultaneous bilateral tubal pregnancy recorded in a Nigerian University Teaching Hospital were reviewed. The incidences were 1 in 68 and 1 in 51 ectopic pregnancies respectively. High twinning rates within the environment and tubal damage from pelvic infections were considered as possible etiologic factors.

Female↗

Neonatal tetanus in babies of women immunized with tetanus toxoid during pregnancy.

In a study of 52 cases of neonatal tetanus admitted to Wesley Guild Hospital, Ilesha, it was found that 17 (33%) of the babies were delivered to mothers who had received adequate tetanus toxoid immunization during pregnancy. The 17 babies were compared with the remaining 35 babies whose mothers had not received tetanus prophylaxis. The case fatality rates in these two groups were 12.5% and 60% respectively (P less than 0.01). This report shows that neonatal tetanus can occur in babies of mothers who were immunized with tetanus toxoid during pregnancy. Maternal immunity may, however, improve the prognosis in such infants.

Female↗

Abortion-related deaths in Ile-Ife, Nigeria: a 12-year review.

Cases of death due to abortions at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria, between January 1977 and September 1988 were reviewed. Abortion accounted for 12.5% of the maternal deaths and the majority (88.9%) were from illegal abortions. The majority (92.6%) of the patients were of low educational status. Both married women and single girls were involved. Instrumentation was employed in 81.5% of the abortions and unqualified personnel were involved in 74.1% of cases of such intervention. Seventeen (63%) of the pregnancies were terminated within the first trimester. Most (96.3%) of the patients were admitted in poor clinical state and 51.8% of them died within 48 h of admission. Sepsis was the commonest cause of death.

Abortion, Illegal↗

Congenital absence of an ovary in a Nigerian woman.

A case of unilateral absence of the left ovary in a 45-year-old grand multiparous Nigerian woman is reported. Congenital absence of a gonad is extremely rare and it indicates a genetic or chromosomal error in the formation of the urogenital ridge.

Female↗

Serum copper, zinc and magnesium in maternal and cord blood at delivery.

Serum concentrations of copper, zinc and magnesium were determined in maternal and cord blood at delivery in term pregnancies among healthy Nigeria women. Maternal serum copper concentration was significantly higher than cord serum concentration. There were no significant differences in maternal and cord serum levels of zinc and magnesium.

Copper↗