Biomedical subjects
Publications and source records attributed to O P Binitie.
Pituitary apoplexy, an uncommon syndrome, presented in a 40-year-old Nigerian with severe impairment of vision and persistent headaches over a 4-month period. Surgical decompression successfully restored his vision. This case is presented with a review of the literature and discussed as the first case seen in this unit since it started 5 years ago.
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A 13-year old Nigerian boy presented with a painless swelling which had grown, over ten years, into a pulsatile monstrous deformity of the left side of the face. Histology of the excised tissue showed a plexiform neurofibroma. It manifested with cutaneous, ocular and bony features. There was also a left eye optic nerve glioma. The case is presented and used to highlight the clinicopathological manifestations of orbital plexiform neurofibroma.
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A small number of patients with congenital hydrocephalus, who have been treated effectively with ventriculoperitoneal shunts, develop progressive increase in abdominal girth, due to cerebrospinal fluid ascites. This abdominal distension can produce respiratory difficulties that require endotracheal intubation and ventilator support. The respiratory difficulties and the abdominal distension were eliminated when the ventriculoperitoneal shunt was converted to a ventriculoatrial shunt in each of the three cases presented in this paper for discussion.
The pattern of congenital malformation of the central nervous system (CNS) as seen in Jos University Teaching Hospital (JUTH) is slightly different from that seen in Europe, Japan and Southern Nigeria. Not all the various types of CNS malformations reported from these centres have been seen in JUTH. Myelomeningocele was the commonest anomaly of the CNS seen and it accounted for more than 60% of all cases. Bilateral talipes equinovarus deformity was the commonest associated anomaly found. No case of anencephaly was seen in this study.