Biomedical subjects

O P Nefed'ev

Publications and source records attributed to O P Nefed'ev.

3 recordsLinked to original sources

PubMed1987

[The verschroben-type defect in torpid schizophrenia].

The authors have studied 30 patients with torpid schizophrenia associated with unfavourable changes of the 'verschroben' type. Only those cases are considered in which manifestations of this defect almost completely determined the clinical picture of the disease. A detailed psychopathological analysis has demonstrated that in patients presenting unfavourable changes of the 'verschroben' type all features characteristic of a mild typical schizophrenic defect or a defect of schizoid structure (autism, emotional changes, bizarre behaviour, paradoxic features in thinking and behaviour, motor peculiarities, disturbances in the sphere of instincts and inclinations) become most expressed. It has also been established that a 'verschroben' type defect forms at later stages of the disease taking a form of evolutional schizophrenia.

Adult↗

PubMed1983

[1 of the variants of stable psychopath-like states in patients with slowly progressing schizophrenia (problem of residual schizophrenia)].

The peculiarities of the clinical course and development of stable psychopathlike states formed during slow-progressive schizophrenia stabilization were studied in 111 patients. Clinically they were attributed to a group of pseudopsychopathy and could be regarded as residual states. Two forming mechanisms of pseudopsychopathy corresponding to the course of endogenic process were singled out: the first one was typified as a characterological shift in paroxysmal course of the disease; the second one as an "amalgamated type" in stagnant course of the disease. Clinical typology of pseudopsychopathies including schizoid, hypochondriac, hyperthymic, hypoparanoic states is presented. Social rehabilitation peculiarities in each case were marked out. The development of endogenic psychoses eventuating in the formation of psychopathlike states is reviewed.

Adult↗

PubMed1982

[Chronic hypomania as a stage of acquired cyclothymia].

The authors examined 28 patients with chronic hypomanic states that form within the bounds of acquired cyclothymia after a schizophrenic psychosis. Two types of the chronic hypomanias were differentiated. The first was hyperthymia, a residual pseudopsychotic state characterized with a combination of cycloid and schizoid features with an invariably elated mood. The patients were energetic, purposeful, indefatigable, and industrious at work. No signs of disease progress were observed for a long time. The second type was subpsychotic hypomania associated with a slow, but still continuing progress of the disease. The elated mood was combined with marked signs of the defect (emotional and intellectual impoverishment, psychopathy-like changes) and still persisting positive symptoms. The activity and ability to adapt themselves enabled these patients to remain sufficiently compensated socially at the new, lower level of the adaptation. Later the psychopathological disorders got deeper, and their scope increased.

Adult↗