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Biomedical subjects

O Périer

Publications and source records attributed to O Périer.

16 recordsLinked to original sources

Petrous bone fractures in children: risk of meningitis, and indication for early Cochlear implant?

The case of a 5 year old boy who had a right petrous bone fracture with right CSF otorrhea and deafness is reported. This child presented, three years after the trauma, a right side otitis media, complicated by meningitis and pneumococcal sepsis, which might have as consequence a left side deafness. The bilateral deafness and the early possibility for cochlear ossification made us decide rapidly on a cochlear implant. Benjamin was then operated for a left side cochlear implant 40 days after contracting meningitis. Two months later, this boy was able to understand a speech without lip reading. Current concepts in the management of petrous bone fractures with CSF otorrhea are reviewed in this report. We also discussed prophylactic attitudes to adopt to reduce the risk of post temporal bone fracture meningitis.

Accidental Falls↗

[The child with defective hearing. Medical, educational, sociological and psychological aspects].

Hearing impairment in children is considered in its various aspects: medical, sociological, psychological, and educational. After a review of the aetiologies, the biological consequences of early auditory deprivation are underlined. The necessity of avoiding or reducing them justifies the efforts made to insure early diagnosis and adequate intervention. Screening and diagnostic techniques are described and illustrated by current results. The particular features of deafness, which stands out among other physical handicaps by the fact that it has given birth to a language, sign language, are stressed and the resulting socio-cultural implications are described. The relationships between deafness and psychology are treated so as to point out that there are no psychological features which characterize deafness, but that it can lead to several cognitive and behavioural consequences. The multiple interventions requested by a child's hearing impairment are detailed, emphasizing that medical or surgical actions must be part of a team work. The physician is called upon to play an essential part in this work, which he can correctly fulfill only by taking into account the sociological, cultural, psychological, educational and prosthetic aspects. The principles of prosthetic adaptation and the different types of prosthetic devices are presented, with special mention of recent and prospective developments. After a historical survey of deaf education, the evolution of ideas and methods from 1972 to 1987 is related, and the presently utilized methods are described and discussed. The different educational structures and their respective merits are outlined, as well as the action in favour of deaf children and their families of social services and parental cooperation.

Audiometry↗

Consequences of auditory deprivation in animals and humans.

An electron microscopic study of the cerebral cortex of mutant deaf mice (Deol's dn gene) has shown differences in synaptic organisation between these mice and normally hearing ones. In the auditory cortex of the deaf mice, there are fewer synapses and these are larger than in the normally hearing, whereas there is no difference between these two categories in the visual cortex. These results are the reverse of those observed by other authors in the occipital cortex of rats raised in an enriched or impoverished environment. In humans, the functional consequences of early hearing loss have been investigated on moderately to severely deaf (60-80 db mean loss) youngsters, who have been tested for their capacity of categorical perception, auditory discrimination, and production of significant contrasts between stop consonants. Categorical perception was absent in all but one subject. Auditory discrimination was poor for both the voiced-voiceless contrast and the place of articulation contrast. In the production experiments, the subjects had greater difficulty in producing the voiced-voiceless than the place of articulation contrasts. The possible relevance of these animal and human studies to cochlear implantation is discussed.

Acoustic Stimulation↗

Clinicopathological study of the visual pathways, eyes, and cerebral hemispheres in 32 cases of disseminated sclerosis.

The pathological study of the cerebral hemispheres and visual pathways in 32 cases of disseminated sclerosis, including 15 cases in which the retinal structures were investigated, lead us to point out: 1) the high frequency of histological lesions of the optic nerves, tracts and radiations; 2) the lack of correlation between the extent of demyelination of the optic nerves and the impairment of visual acuity that is mainly related to axonal lesions; 3) the relative high frequency of pathological sheathing of retinal veins; and 4) the high proportion of shadow plaques in the cerebral hemispheres in cases with clear-cut relapses and remissions.

Adult↗

Temporal lobe oligodendroglioma developing from infancy into adulthood.

Clinical, radiological, surgical, and histological features are reported for a patient with a temporal lobe oligodendroglioma that had developed in infancy and was diagnosed and partially resected at age 10. The patient is presently 24 years old and still well. To the best of our knowledge this is the first report of an oligodendroglioma with probable onset at 5 months of life and satisfactory course over 24 years.

Adolescent↗