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O Pichler

Publications and source records attributed to O Pichler.

At least 19 recordsLinked to original sources

[Computer-assisted analysis of ultrasound sequences of the left ventricle for determining ejection fraction].

The present study describes an automatic procedure for calculating the ejection fraction on the basis of ultrasound images. This procedure is divided into three steps, and programmed in C/UNIX. In an initial step, an algorithm, known as sequence analysis, is used to identify the enddiastolic and endsystolic images from a series of ultrasound images. With the use of a template matching procedure for calculating displacement vectors, a method has been developed for the first time for analysing moving images for identification purposes. The subsequent image analysis employs various filter processes for noise suppression, contrast enhancement, image sharpening, edge detection and segmentation. On the basis of the geometrical data of the segmented left ventricle obtained in this way the respective volumes and ejection fraction are calculated. To validate this automatic procedure, the series of ultrasound images were examined by a cardiologist. It was found that the identification of the endsystolic and enddiastolic image was correct, and that there was good agreement between the automatically determined and manually determined ejection fraction.

Algorithms↗

[Metabolism studies with coffee and caffeine in healthy subjects, diabetics and patients with liver disease].

Peroral application of caffeine or theophylline causes a significant increase of the free fatty acids and the free glycerol of the serum; blood sugar and cholesterol are not influenced. FFA and free glycerol decrease during the day by food intake, blood sugar and triglycerides rise. The ingestion of coffee (1-3 cups) does not influence fat and carbohydrate metabolism. To induce a significant increase of lipolysis and of serum triglyceride levels high caffeine doses (1000 mg) are required. Summarizing the data presented, the authors conclude that coffee intake (at dosages compatible with normal nutrition) does not deteriorate glucose tolerance and does not interfere with the fat metabolism. Our findings are confirmed by epidemiologic investigations which have shown that coffee intake is no risk factor for myocardial infarction.

Caffeine↗