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Biomedical subjects

O Pollak

Publications and source records attributed to O Pollak.

8 recordsLinked to original sources
PubMed1980

The dose of diphtheria toxoid in combined vaccines and their use in children.

The currently recommended immunization scheme consists of diphtheria, tetanus and pertussis vaccine (DTP) given at the ages of 3, 4 1/2 and 6 months, followed by a reinforcing dose of the same vaccine at 18 months, and one of diphtheria and tetanus vaccine (DT) before school entry. Children injected according to this scheme may be over-immunized. The amount of diphtheria toxoid (25 Lf per dose) contained in DTP should not be reduced, because some of the children missing the third primary dose would be left unprotected until after the 18-month injection had been given. It is likely that the 18-month dose could be omitted without great danger if the preschool booster dose were assured, and more than likely that preschool boosting with DT is unnecessary if the full course, including the 18-month dose, has been given. Reinforcing doses of tetanus toxoid need not be given as often as every 10 years. They are probably not required except in the case of injury and may, even then, be omitted if less than 5 years have lapsed since the completion of basic immunization, or since the injection of the last booster dose. Non-adsorbed diphtheria and tetanus toxoids may be the preparations of choice whenever immunity has to be reinforced.

Child↗
PubMed1980

Serum antibody levels after immunization with trivalent oral poliovirus vaccine.

The antibody titres to the polioviruses after three doses of trivalent oral poliovirus vaccine were assessed in 77 Coloured children aged 3-9 months. Neutralizing antibody titres of 1 in 10 or greater to all three types were found in 59 (77%) of all children. The remaining 18 children lacked demonstrable antibody to one or more of the polioviruses. Antibody to types 1 and 3 was most commonly lacking. The possible reasons for the failure of vaccination in so many children is discussed. Studies of the effect of further doses of vaccine on serum antibody levels are recommended.

Antibodies↗
PubMed1979

Awareness and disengagement in cancer patients.

The authors found that cancer patients (N = 44) did not differ from patients with other chronic illnesses (N = 27) with respect to awareness of their condition or ratings on an unobtrusive, nonverbal measure of disengagement. Cancer patients who were aware were more engaged than those who were not, but this was equally true for the noncancer patients. Awareness, for the cancer patients, was not associated with frequency of visiting or with living for a longer or shorter period than expected. There was a significant interaction, however, in that patients who were aware lived longer if they were engaged, whereas patients who were unaware lived longer if they were disengaged. Caution and judgment should be exercised in sharing information with terminally ill patients because awareness may be beneficial for some but not for all.

Aged↗