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O R McIntyre

Publications and source records attributed to O R McIntyre.

96 records · Page 6Linked to original sources
PubMed1965

Characteristics of non-cholera Vibrios isolated from cases of human diarrhoea.

Eighty-two organisms tentatively identified as non-cholera vibrios were isolated from cases of diarrhoea occurring in East Pakistan. In 19 well-studied cases they were the predominant organism recovered, and a rise in agglutinating-antibody titre was found in six of these cases.Because of this additional evidence that non-cholera vibrios cause diarrhoeal disease, it was necessary to evaluate simple screening tests as a means of recognizing them. It was found that all organisms that produced a gelatinase "zone", had typical vibrio morphology on microscopic examination, produced colonies showing a characteristic picture when examined by oblique light microscopy, and gave a positive "string" test were vibrios. Agglutination tests with vibrio O group I antiserum and with antirough vibrio serum distinguished the organisms from Vibrio cholerae. Since these organisms may be discarded by enteric diagnostic procedures directed mainly towards the isolation and identification of Salmonella and Shigella, it is recommended that the screening tests for these organisms be carried out in cases of diarrhoea of unknown etiology.

Diarrhea↗
PubMedDate not supplied

Acute leukemia and residential proximity to potential sources of environmental pollutants.

Possible associations between location of residence and acute leukemia risk were investigated in a study of 610 newly diagnosed patients, aged 18-79 y, and 618 population controls. There was an association between ever living within 5 miles (8 km) of an industrial plant and leukemia risk, with adjusted odds ratios (ORs) of 1.4 (95% confidence interval [95% CI] = 1.0-1.9) for all acute leukemias combined, 1.4 (95% CI = 1.0-2.0) for acute myeloid leukemia, and 1.7 (95% CI = 1.0-2.7) for acute lymphocytic leukemia. Odds ratios increased with decreasing distance from industrial sites, but a gradient with duration of residence was seen only among those less than age 60 who had lived within a mile of any industry. Suggestive associations were also observed for residence near specific industries, but the number of individuals living near any one industry was small.

Adolescent↗
PubMedDate not supplied

Case report: circulating anticoagulant, autoimmune hemolytic anemia and malignant lymphoma.

A circulating anticoagulant of the type often seen in systemic lupus erythematosus, an autoagglutinin and a Coombs-reactive autoantibody were identified in a patient who had the subsequent diagnosis of poorly differentiated diffuse lymphocytic lymphoma. Evidence indicated that the red cell autoantibodies did not possess anticoagulant properties. The red cell autoantibodies as well as the anticoagulant disappeared following corticosteroid therapy. It is probable that the anticoagulant is a manifestation of autoimmunity. The coexistent autoimmune and lymphoproliferative abnormalities in this patient resemble certain animal models in which evidence exists for a viral etiology of the autoimmune and lymphoproliferative disorders.

Adult↗