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Biomedical subjects

O Ramirez

Publications and source records attributed to O Ramirez.

At least 37 records · Page 2Linked to original sources
PubMed1982

Multiple granular cel tumors of the gallbladder and biliary tree. Report of a case.

Granular cell tumors are benign lesions that usually appear in the skin, oral activity, and mucous membrane. Occasionally, they will appear in visceral organs, and cause signs and symptoms similar to those of other organ-related diseases. We studied a patient with granular cell tumors of the common bile duct whose clinical appearance mimicked that of cholecystitis with cholelithiasis. Recognition of granular cell tumors on frozen section will allow surgical resection with probable cure.

Adult↗
PubMed1977

The effects of hypophysectomy upon DNA synthesis in rat oral epithelium.

Ten hypophysectomized and 10 normal female albino rats, 50-days-old, were kept for 5 days and treated with tritiated thymidine 1 hour before sacrifice of the animals. The animals were weighed and the histomorphology of the palate epithelium was studied including the thickness, cell density, and DNA labeling index. The hypophysectomized rats failed to gain weight after 5 days. The palatal epithelium showed a normal morphology indicating the hypophysectomy allowed for differentiation of squamous epithelium. There was a significant reduction in the thickness of the epithelium and a reduced cell density. This was attributed to a significant decrease in DNA synthesis. The epithelial cells were lost from the surface without adequate replacement due to an expected depression in mitotic activity. DNA synthesis may be depressed due to reduced ATP synthesis resulting from suboptimal glucose metabolism and depression in protein synthesis.

Amino Acids↗
PubMed1969

Creatinine clearance in renal disease. A reappraisal.

To determine the validity of endogenous creatinine clearance as a measure of glomerular filtration rate in patients with renal disease 308 simultaneous determinations of inulin clearance and endogenous creatinine clearance were reviewed and analysed. The ratio of creatinine clearance/inulin clearance increased progressively with the decline in inulin clearance, while the finding of a normal endogenous creatinine clearance masked a definite but mild decrease of glomerular filtration rate in 42% of the patients and a moderate decrease of glomerular filtration rate in 23%. This indicates that with declining glomerular filtration rates the endogenous creatinine clearance progressively overestimates actual glomerular filtration rates. Hence a single determination of creatinine clearance can be misleading as a screening measurement of glomerular filtration rate.

Adult↗