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Biomedical subjects

O S RAY

Publications and source records attributed to O S RAY.

11 recordsLinked to original sources
PubMed1964

TIME FACTORS IN INTERHEMISPHERIC TRANSFER OF LEARNING.

Single-trial interhemispheric transfer of a discrimination task engram was studied by eliciting spreading depression unilaterally during acquisition of the discrimination. Complete transfer to the untrained side occurred after one trial with both hemispheres functional, if 10 minutes elapsed between this trial and the elicitation of spreading depression in the trained side. If depression was elicited 15 seconds after the trial no transfer occurred. correct response highly probable.

Brain↗
PubMed1961

A quantifiable behavioral correlate of psychotogen and tranquilizer actions.

A representative psychotogen, lysergic acid diethylamide (LSD-25), in doses small enough to be devoid of gross effects, increases response latency in rats to a tone indicating the availability of water reward; this effect is greatly reduced by prophylactic administration of a representative phenothiazine tranquilizer, chlorpromazine (CPZ), in doses that per se do not affect performance. The nature of the chlorpromazine action and its competition with lysergic acid diethylamide is revealed by the effects of chlorpromazine in larger doses.

Animals↗
PubMed1959

Self-regulation of brain-stimulating current intensity in the rat.

A modification of the self-stimulation technique of Olds enabled rats to regulate and maintain at a preferred level the amount of brain-stimulating current they received as reinforcement for lever pressing. The method used two levers to deliver brief brain shocks: each response at one lever increased the current intensity a small step and each response at the other lowered it one step.

Animals↗