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O S Shkrob

Publications and source records attributed to O S Shkrob.

119 records · Page 7Linked to original sources
PubMedDate not supplied

[Magnetic resonance tomography of the adrenals in the diagnosis of total and partial hypercorticism].

The paper is devoted to the use of a new method of nuclear magnetic resonance tomography (MR tomography) in the diagnosis of diseases of the adrenal glands developing with the syndrome of total and partial hypercorticism. A MR tomograph with resistive magnet (0.234 T) was employed. Altogether 25 patients were examined (21 with Itsenko-Cushing disease of various degrees of severity, 2 patients with Itsenko-Cushing syndrome and 2 patients with aldosteronoma). MR tomography was shown to possess a high informative value permitting the assessment of a type of adrenal changes without irradiation of a patient. In combination with routine methods of examination (hormonal investigation, retropneumoperitoneum, x-ray computerized tomography) MR tomography makes it possible to improve considerably the diagnosis of Itsenko-Cushing disease and to specify tumor sizes and tumor growth type.

11-Hydroxycorticosteroids↗
PubMedDate not supplied

The effect of diazane on the proliferation of human tumor cells.

The effect of the antitumorigenic agent diazane (1,2-bis-diazoacetylethane) in the cells of 30 human tumors cultured in vivo in diffusion chambers, implanted intraperitoneally into mice. Twenty-four hours after the introduction of diazane, a decrease in the proportion of DNA-synthesizing cells and the intensity of DNA synthesis to 30--50% of the control values is observed. By 48 hours, the values of these parameters had returned to the initial level.

Antineoplastic Agents↗