Angiotensin-induced drinking: sexual differences.
The dipsogenic effect of Angiotensin-II (A-II) in relation to sexual variables was studied. It was found that Angiotensin-II administered SC constitutes a stimulus which induces more drinking in females than in males. Moreover, the adult females show maximum sensitivity to A-II during proestrus. The males and females castrated at birth, and females androgenized at birth, drink similar volumes of water after A-II SC injection. The pattern of stimulated intake is different in the two sexes, and appears to depend upon the development of the rats.
Angiotensin II↗