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Biomedical subjects

O Schweiger

Publications and source records attributed to O Schweiger.

At least 19 recordsLinked to original sources
PubMed2004

Spatial genetic structure in a metapopulation of the land snail Cepaea nemoralis (Gastropoda: Helicidae).

Habitat fragmentation is a major force affecting demography and genetic structure of wild populations, especially in agricultural landscapes. The land snail Cepaea nemoralis (L.) was selected to investigate the impact of habitat fragmentation on the spatial genetic structure of an organism with limited dispersal ability. Genetic and morphological patterns were investigated at a local scale of a 500 m transect and a mesoscale of 4 x 4 km in a fragmented agricultural landscape while accounting for variation in the landscape using least-cost models. Analysis of microsatellite loci using expected heterozygosity (HE), pairwise genetic distance (FST/1-FST) and spatial autocorrelograms (Moran's I) as well as shell characteristics revealed spatial structuring at both scales and provided evidence for a metapopulation structure. Genetic diversity was related to morphological diversity regardless of landscape properties. This pointed to bottlenecks caused by founder effects after (re)colonization. Our study suggests that metapopulation structure depended on both landscape features and the shape of the dispersal function. A range of genetic spatial autocorrelation up to 80 m at the local scale and up to 800 m at the mesoscale indicated leptokurtic dispersal patterns. The metapopulation dynamics of C. nemoralis resulted in a patchwork of interconnected, spatially structured subpopulations. They were shaped by gene flow which was affected by landscape features, the dispersal function and an increasing role of genetic drift with distance.

Animals↗
PubMed1987

[Incidence of lung fibrosis in Hungary].

Epidemiological data of patients with lung fibrosis being registered in dispensaries are demonstrated. Three groups of fibrosis patients are registered: lung fibrosis of known origin, lung fibrosis associated with systemic disease and lung fibrosis of unknown origin. In 1984 prevalence was 22.7/100,000. Incidence was the lowest in systemic diseases and the highest in lung fibrosis of unknown origin.

Adolescent↗
PubMed1984

[Measurement of sputum viscosity with the Jenssen viscometer].

The authors measured the viscosity of sputum with a Jenssen type capillary viscometer. The repeated assessment of the viscosity of the same sample of sputum showed that the results are reproducible and the instrument does not disrupt markedly the structure of the sputum. After measuring the viscosity of 35 patients with different types of pulmonary disease the authors state, in accordance with the data found in literature, that the measurement of the viscosity of sputum by itself cannot help in the differential diagnosis of pulmonary diseases. The authors suggest the determination of the Biochemical constituents of sputum to supplement the measurement of the viscosity of sputum.

Bronchitis↗
PubMed1980

[CO2-production of circulating lymphocytes in the presence of a sarcoidosis extract in patients with sarcoidosis (author's transl)].

The CO2-production of circulating lymphocytes of patients with sarcoidosis and other diseases was investigated in presence of an sarcoidosis extract and without it. In 32 of 36 patients with sarcoidosis an elevated CO2-production of the lymphocytes was observed in presence of a sarcoid extract, whereas it happened only in 3 of 26 cases of a control group.

Carbon Dioxide↗
PubMed1980

[Differences in the levels of serum immunoglobulin E determined by the competitive radio-immuno-sorbent and the paper-radioimmuno-sorbent methods: Removal of these differences by pretreatment of sera with polyethylene glycol (author's transl)].

The serum IgE of patients with chronic nonspecific lung diseases was determined with the competitive radio-immuno-sorbent and the paper-radio-immuno-sorbent methods (Phadebas). Some samples showed markedly higher values with the competitive radio-immuno-sorbent than with the paper-radio-immuno-sorbent method. These discrepancies were abolished by pretreatment of the sera: polyethylene glycol 6000 (final concentration 35 g/l) was added, followed by centrifugation at 0 degrees C for 30 min at 20 000 g, and IgE was determined in the supernatant. This treatment had no effect on the values of the paper-radio-immuno-sorbent method, but the values of the competitive radio-immuno-sorbent method were decreased so that the two values agreed within the experimental confidence limits.

Binding, Competitive↗