Biomedical subjects
Publications and source records attributed to O Stoianov.
The authors share their experience in the operation of the maxillary sinuses by using osteoplastic graft. This technique allows saving or reconstructing of the front sinus wall. It makes possible isolation of soft tissues from the upper maxilla and preventing infection and other complications. We didn't find any pathological changes in the 2 year follow-up period. We recommend and find this technique reliable.
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Calcium-phosphor metabolism was studied in patients with active acromegaly with or without osteoporosis, mean age 45.2 +/- 11.4 years and mean duration of the basic disease 5.52 +/- 3.6 years. No significant deviations and no direct relation with the high serum growth hormone and prolactin levels were found. The normal basic secretion of the calcitrophic hormones--parathyroid hormone and calcitonin and their normal response to the hypercalcemia after intravenous calcium load of the patients with and without osteoporosis reject their direct participation in the pathogenesis of osteopenia. The changed skeletal sensitivity to calcitrophic hormones closely connected with the patients' age and the duration of the basic disease in combination with many other factors probably plays a major role in the pathogenesis of osteopenia.