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Biomedical subjects

O Trelles-Salazar

Publications and source records attributed to O Trelles-Salazar.

2 recordsLinked to original sources

An image-processing approach to dotplots: an X-Window-based program for interactive analysis of dotplots derived from sequence and structural data.

We present an approach to the study of the relationships between biological sequences and structures applying image analysis methods to dotplots. We introduce a set of analytical tools based on different types of digital image-processing filters that are new within the context of dotplots. We have reformulated some of the usual approaches in dotplot analysis as mathematical operations on images within the framework of mathematical morphology. An X-Window-based implementation of this new approach has been developed and is available by anonymous FTP.

Data Interpretation, Statistical

On an efficient parallelization of exhaustive sequence comparison algorithms on message passing architectures.

We present a new parallel computing approach to the case of exhaustive sequential sequence comparison algorithms on message-passing architectures. In this context a modification of guided self-scheduling as well as efficient buffering strategies are presented. We discuss two specific implementations, one on the Paramid parallel computer, and the other on a cluster of workstations running PVM. In both cases the parallel performance is higher than with any other method presented so far. The code is public domain and can be obtained by anonymous ftp at ftp.cnb.uam.es.

Algorithms